^<13>C MR Imaging of Methionine-rich Gliomas at 4.7T : A Pilot Study
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概要
- 論文の詳細を見る
We explored the feasibility of using carbon-13 (13C) magnetic resonance imaging (13C-MRI) to depict 13C-labeled methionine-enriched gliomas at 4.7 tesla. We transplanted 2 types of glioma cells separately to 2 subcutaneous tissue sites on the backs of mice weighing 15 to 20 g. After confirming tumor growth, we used 13C-MRI and 1H-MRI to scan 4 mice that had been administered 13C-labeled methionine and 2 control mice. 13C-MRI of all 4 transplanted mice administered with 13C-labeled methionine revealed 2 areas of hyperintensity that corresponded to the tumor sites on 1H-MR images, but no such areas were visualized in transplanted controls. Our data suggest that 13C-MRI can show the accumulation of 13C-labeled tracer by gliomas.
- 日本磁気共鳴医学会の論文
- 2011-06-01
著者
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Yamashita Yasuyuki
Department Of Radiology Kumamoto University
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Yamashita Yasuyuki
熊本大学 医学薬学研究部放射線診断学
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Yanaga Yumi
熊本大学 医学薬学研究部放射線診断学
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平井 俊範
熊本大学・医学部保健学科
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Hirai Toshinori
熊本大学 放医
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山下 康行
熊本大学 大学院放診
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Hirai Toshinori
Department Of Radiology Amakusa Medical Center
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Kudo Mareina
Department Of Neurosurgery Faculty Of Medical And Pharmaceutical Sciences Kumamoto University Gradua
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山下 康行
熊本城医療センター
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Yamaguchi Yasuo
Department Of Surgery Ii Kumamoto University Medical School
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山下 康行
熊本大 医 放射線医学
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Tsuiki Hiromasa
Department Of Neurosurgery Kumamoto University School Of Medicine:(present Office)department Of Neur
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Yamashita Yasuyuki
Department Of Diagnostic Imaging Faculty Of Medical And Pharmaceutical Sciences Kumamoto University
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Yamashita Yasuyuki
Department Of Diagnostic Radiology Graduate School Of Medical Sciences Kumamoto University
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Yamashita Yasuyuki
Department Of Diagnostic Radiology Kumamoto University Postgraduate School
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Nakamura Hideo
Department Of Cardiovascular Medicine Kyoto Prefectural University Of Medicine
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Nakamura Hideo
Department Of Neurosurgery Graduate School Of Medical Sciences Kumamoto University
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Yamaguchi Yasuo
Department Of Diagnostic Radiology Graduate School Of Medical Sciences Kumamoto University
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SASAO Akira
Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University
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Sasao Akira
Department Of Diagnostic Radiology Graduate School Of Medical Sciences Kumamoto University
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IRIGUCHI Norio
Division of Multimedia Information Processing Center, Kumamoto University
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SASAO Ako
Department of Forensic Medicine, Graduate School of Medical Sciences, Kumamoto University
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Nakamura Hideo
Department Of Cardiology Kyoto Prefectural Yosanoumi Hospital
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Kudo Mareina
Department Of Neurosurgery Kumamoto University
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Iriguchi Norio
Division Of Multimedia Information Processing Center Kumamoto University
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HIRAI Toshinori
Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University
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