Elucidating Conservation of Genes in Multiple Genomes Based on Graphs Configured by Bidirectional Best-Hit Relationships

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概要

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• Gene classification based on orthologous relations is an important problem to understand species-universal or species-specific conservation of genes in genomes associated with phenotype in species. In the present study, we proposed a classification system of genes based on configuration of networks concerning bidirectional best-hit relations (called orthologous relation group), which makes it possible to compare multiple genomes. We have applied this method to five Bacillus species (B. subtilis, B. anthracis, B. cereus, B. halodurans, and B. thuringiensis). With regards to the the five species, 4,776 orthologous relation groups have been obtained, and those are classified into 113 isomorphic groups. An isomorphic group may contain only orthologs or a combination of orthologs and paralogs. Gene functions and the conservativeness are discussed in view of configuration of orthologous relation groups.

• 一般社団法人情報処理学会の論文
• 2006-11-15

著者

• KANAYA Shigehiko

  Graduate School of Information Science, Nara Institute of Science and Technology

• ALTAF-UL-AMIN Md.

  Graduate School of Information Science, Nara Institute of Science and Technology

• KUROKAWA Ken

  Department of Biological Information, Tokyo Institute of Technology

• Kurokawa Ken

  Dep. Of Biological Information Tokyo Inst. Of Technol.

• Altaf-ul-amin Md.

  Graduate School Of Information Science Nara Institute Of Science And Technology

• Altaf-ul-amin Md.

  Nara Institute Of Science And Technology

• MAENO HIJIRI

  Nara Institute of Science and Technology, Graduate School of Information Science

• SHINBO YOKO

  Nara Institute of Science and Technology, Graduate School of Information Science

• KUROKAWA KEN

  Nara Institute of Science and Technology, Graduate School of Information Science

• OGASAWARA NAOTAKE

  Nara Institute of Science and Technology, Graduate School of Information Science

• KANAYA SHIGEHIKO

  Nara Institute of Science and Technology, Graduate School of Information Science

• Altaf‐ul‐amin Md.

  Nara Institute Of Science And Technology Graduate School Of Information Science

• Kanaya Shigehiko

  Nara Institute Of Science And Technology Graduate School Of Information Science

• Maeno Hijiri

  Nara Institute Of Science And Technology Graduate School Of Information Science

• KANAYA Shigehiko

  RIKEN Plant Science Center

• Ogasawara Naotake

  Graduate School Of Information Sci. Nara Inst. Of Sci. And Technol.

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