Histochemical Demonstration of Acid Phosphatase in a Human Retinal Pigment Epithelial Cell Line
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概要
- 論文の詳細を見る
The retinal pigment epithelium (RPE) has numerous lysosomes and shows the highest acid phosphatase activity among eye tissues. In an established cell line of human RPE (K-1034), acid phosphatase activity, as a lysosome marker was investigated histochemically to evaluate the maintenance of original RPE characteristics. Even after 100 passages, RPE cells showed remarkable enzyme activity, and had numerous electron-dense bodies which were confirmed to be lysosomes. These results show that this cell line can maintain one of the vital functions of the RPE and provide useful experimental material for functional studies of the human RPE.
- 東海大学の論文
著者
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TANAKA Yasuhiko
Department of Cardiology, Shizuoka Children's Hospital
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OBAZAWA Hajime
Eye Research Institute of Cataract Foundation
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Kigasawa Kazuteru
Department Of Ophthalmology School Of Medicine Tokai University
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Obazawa H
Tokai Univ. School Of Medicine
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Obazawa Hajime
Department Of Ophthalmology School Of Medicine Tokai University
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Tanaka Yasuhiko
Department Of Ophthalmology School Of Medicine Keio University
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Tanaka Y
Department Of Ophthalmology School Of Medicine Keio University
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SOUSHI Sumi
Department of Ophthalmology, Tokai University Tokyo Hospital
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Soushi Sumi
Department Of Ophthalmology Tokai University Tokyo Hospital
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Tanaka Yasuhiko
Department Of Applied Chemistry Graduate School Of Engineering Kyushu University
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