スリランカ産ウエステルマン肺吸虫Paragonimus westermaniの感染によりネコ肺に発生した病変の病理組織学的研究

概要

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A pathohistological study on Paragonimus westermani from Sri Lanka was performed on infected cats after the autopsy. Sclerosis was observed in the cats' lungs. Furthermore, the grey worm cysts were recognized on the surface of the lungs of the infected cats. Normally, a pair of adult worms of P. westermani parasitize in each of the lung cysts, and the walls of the cysts were covered with squamous cell metaplasia of bronchus epithelial cells.A remarkable infiltration by various inflammatory cells such as histiocytes, lymphocytes and plasma cells had occurred in the cysts of the host lung, leading to the formation of granulomas. The eggs were scattered around the inflammatory cells, which were surrounded with a small number of eosinophils. This study supports their findings of Yokogawa and Blair et al. described in the reports on human paragonimiasis. The present study is an animal model of human paragonimiasis to elucidate the disease mechanism.
高知学園短期大学の論文
2005-03-15