下垂体腺腫におけるGH,ACTH,PRLの免疫組織化学的検索

概要

論文の詳細を見る
In order to identify the localization of GH, ACTH and PRL, nineteen pituitary adenomas were studied by immunohistochemical methods. The presence of immunoreactive GH and PRL correlated well with clinical history and serum levels.Many PRL cells were seen in the tissues of thirteen cases. Most of the cases showed amenorrhea or galactorrhea with hyperprolactinemia. From the symptoms, these cases were diagnosed as prolactinoma. Four out of nineteen cases presented acromegaly with many GH cells, showing that these cases can be diagnosed as the GH producing pituitary adenomas. It was also found that these GH cells were mostly acidphil. In two cases, immunoreactive cells were not seen. These two, therefore, were considered to be adenoma of hypopituitarism. The results demonstrated that immunohistochemical staining was the most accurate morphological method and useful diagnostic features.
高知学園短期大学の論文
1988-08-25