雌ラットのカルシウム,リンおよびマグネシウム出納に及ぼす飼料中カゼインまたは分離大豆たん白質レベルの影響

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The experiment was carried out to observe the effect of dietary protein quality and quantity on urinary calcium (Ca), phosphorus (P) and magnesium (Mg) excretions in female rats. Casein and soy protein isolates were used as a protein source, and a protein content in the diet was 20% or 40% respectively. Female Fischer-strain rats of 4 weeks of age were divided into groups of 20% casein diet (C20), 40% casein diet (C40), 20% soy protein isolate diet (S20) and 40% soy protein isolate diet (S40), and were fed one of the experimental diets for 25 weeks. In 1, 13 and 25 weeks, Ca, P and Mg balance studies were done. After the 25 weeks balance studies, rats were killed and the Ca, P and Mg content of serum, kidney and right femur were determined. The results were as follows : 1) Body weight gain was not significantly different among the four groups. 2) Calcium and P absorption decreased with age but were not affected by the diets, whereas C 40 group exhibited higher urinary Ca, P and Mg excretions. Ca, P and Mg retention also decreased with age. 3) Soy protein isolate diets always indicated high Mg retention than the casein diets. On the other hand,C40 group showed the highest urinary Mg excretion and gave nagative Mg balance at 25 weeks. 4)The weight of fat-free femur, the ash content of per gram of femur, and the Ca content and Ca/P ratio of femur did not show a significant difference among the four groups. But the Ca content of femur per 100 g body weight significantly decreased in the C40 group than in the S40 group. 5)The kidney weights of the 40% protein diet groups significantly increased than the 20% protein diet groups. The calcium and Mg content of per gram of the kidney in the 40% protein diet groups significantly decreased than the 20% protein diet groups.
東京聖栄大学の論文
1990-12-20

雌ラットのカルシウム,リンおよびマグネシウム出納に及ぼす飼料中カゼインまたは分離大豆たん白質レベルの影響

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