ネコノミに対する幼若ホルモン活性化合物 pyriproxyfen, methoprene の効果

概要

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Inhibitory effects of two JHAs, pyriproxyfen and methoprene, on embryonic and larval development of the cat flea, Ctenocephalides felis, were determined by laboratory test. The inhibitory effects of the JHA on cocoon formation and larval-adult development when incorporated into the larval-rearing media of 1- to 3-day-old larvae were investigated. The IC_<50> values of pyriproxyfen were 0.0056ppm for cocoon formation and 0.00017ppm for larval-adult development, while the IC_<50> values of methoprene were 0.014 and 0.00032ppm, respectively. The ovicidal effects were observed when flea eggs within 24-hr-old were exposed continuously on filter paper treated with pyriproxyfen or methoprene, showing that the ID_<50> were 0.045 and 0.182μg/(cm)^2,respectively. Adult fleas were exposed to pyriproxyfen, then fed on a cat to investigate the ovicidal effect on flea eggs. The egg hatching was inhibited immediately. The partial inhibition (more than 50% inhibition) of egg hatching lasted for six days after treatment. The inhibitory effects of pyriproxyfen on egg hatching when treated on the fur of cats at dosages of 4 and 12mg per cat were investigated. The treatment at the lower dosage completely inhibited the egg hatching for 11 days and at the higher dosage for 18 days. In the latter case, the percentage of hatching was considerably less than that of the control throughout the 2 months after treatment.
1994-09-15