Studies on Antitumor Activity of Some Fractions from Basidiomyces. I. An Antitumor Acidic Polysaccharide Fraction of P. ostreatus (Fr.) QUEL

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概要

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• An antitumor active aqueous extract was obtained from P. ostreatus (Fr.) QUEL. The fractionation by ethanol precipitation, ultrafiltration with molecular sieve membrane and adsorption on DEAE-Sephadex were effective to purify an antitumor active fraction A_5 as one spot on a electrophoresis, and to isolate another active fraction A_3 and an inactive fraction A_6. The active fraction A_5 and A_3 were constituted of macromolecular polysaccharide, but molecular size of the inactive fraction A_6 was smaller than those of the active fractions. The main component sugar was glucose in the fraction A_5 and A_3,but it was galactose in the fraction A_6. The fraction A_5 differed from the fraction A_3 in a point of including acidic sugar.

• 公益社団法人日本薬学会の論文
• 1972-06-25

著者

• 野田 雅子

  National Cancer Center Research Institute

• 池川 哲郎

  National Cancer Center Research Institute

• 福岡 文子

  National Cancer Center Research Institute

• 吉岡 佑子

  Chemotherapy, National Cancer Center Research Institute

• 池川 哲郎

  国立がんセ 研

• 池川 哲郎

  国立がんセンター研究所:金沢大学教育学部

• 池川 哲郎

  金沢大学教育学部

• 吉岡 佑子

  National Cancer Center Research Institute

• 吉岡 佑子

  Chemotherapy National Cancer Center Research Institute

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