Pyrimidine Derivatives. VIII. One-Step Synthesis of 3,4-Dyhydro-pyrimido[6,1-c][1,4]oxazine Derivatives by Reactions of 5-Bromo-1-(2-bromoethyl)-6-bromomethyl-2,4-(1H, 3H)-pyrimidinedione with Sodium Alkoxides and 2-Nitropropane

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概要

• 論文の詳細を見る

• The reaction of 5-bromo-1-(2-bromoethyl)-6-bromomethyl-3-methyl-2,4(1H, 3H)-pyrimidinedione (1) with the sodium alkoxide/2-nitropropane system and that of the dinitrate (2) of 5-bromo-1-(2-hydroxyethyl)-6-hydroxymethyl-3-methyl-2,4(1H, 3H)-pyrimidinedione with sodium alkoxide provide convenient routes to a wide range of 3,4-dihydro-pyrimido[6,1-c][1,4]oxazine derivatives (3) in excellent yields.

• 公益社団法人日本薬学会の論文
• 1992-10-25

著者

• 古川 淳

  School Of Pharmaceutical Sciences Nagasaki University

• 木下 敏夫

  School of Pharmaceutical Sciences, Nagasaki University

• 宇賀 美帆

  School of Pharmaceutical Sciences, Nagasaki University

• 谷元 陽子

  School of Pharmaceutical Sciences, Nagasaki University

• 大石 清美

  School of Pharmaceutical Sciences, Nagasaki University

• 木下 敏夫

  School Of Pharmaceutical Sciences Nagasaki University

• 谷元 陽子

  School Of Pharmaceutical Sciences Nagasaki University

• 宇賀 美帆

  School Of Pharmaceutical Sciences Nagasaki University

• 大石 清美

  School Of Pharmaceutical Sciences Nagasaki University

関連論文

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