A Novel and Stereoselective Synthesis of (E)-1-Acylbutadienes from 1-Chloroalkyl Phenyl Sulfoxides and 4-(Phenylthio)butanal through α, β-Epoxy Sulfoxides
スポンサーリンク
概要
- 論文の詳細を見る
The alkylation of 4-(phenylthio)butanal with 1-chloroalkyl phenyl sulfoxides gave chlorohydrins, which were tereated with excess thiophenolate in tert-butanol to afford α, δ-bis(phenylthio)ketones in good overall yield. On treatment with m-chloroperbenzoic acid followed by pyrolysis in refluxing toluene, the bis(phenylthio)ketones gave 1-acylbutadienes in moderate yield with high E-stereoselectivity.
- 社団法人日本薬学会の論文
- 1988-03-25
著者
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佐藤 毅
東京理科大学理学部
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佐藤 毅
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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山川 浩司
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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本橋 重康
Department of Pharmacy, College of Science and Technology, Nihon University
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山川 浩司
東京理科大学
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山川 浩司
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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山川 浩司
東京理大
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Satoh T
Department Of Applied Chemistry Faculty Of Engineering Osaka University
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Sato Toshiyuki
Yamagata Research Institute Of Technology
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本橋 重康
Department Of Pharmacy College Of Science And Technology Nihon University
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