ネジキLyonia ovalifolia DRUDE var.elliptica HAND.-MAZZ.の成分研究(第15報) : 花の成分についてその2 : Terpenoid成分特に3-O-p-Hydroxy-trans-cinnamoylmaslinic Acidとその関連化合物の合成

概要

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A new compound (I), isolated from the benzene extract of the flowers of Lyonia ovalifolia var. elliptica, was studied through the schemes shown in Fig. 1 and 2,and the structure of I was elucidated as 3-O-p-hydroxy-trans-cinnamoyl ester of maslinic acid. The methyl ether methyl ester acetate of I was synthesiged starting from maslinic acid and p-hydroxy-trans-cinnamic acid. Eleven related compounds of I, cinnamoyl and p-methoxycinnamoyl esters of six triterpenoids were synthesized, some data of which are given in Table I. Two crystalline substances, A and B, were newly isolated from the benzene extract of the flowers. Substance A, C_30H_50O_5・1/2 H_2O, is a new compound but its structure has not been defined. Substance B was identified as lyoniol-A, the main toxic principle of the leaves of this plant.
公益社団法人日本薬学会の論文
1971-11-25