人型結核菌体熱水抽出物質に関する研究(第1報)多糖成分の化学構造

概要

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The structures of polysaccharides obtained from hot water extract of Mycobacterium tuberculosis strain Aoyama B were investigated. The polysaccharides fractionated by moleculer sieve-, ion exchange- and affinity-chromatographies and ethanol precipitation were analysed. Main polysaccharides clarified from the results are ; 1) arabinomannan in which arabinan core and mannan core coupled alternately, having average molecular weight of about 12000,2) mannan with many side chains and average molecular weight of about 5000,3) a mixture of lipoarabinomannan and lipomannan with fatty acid ester of about 18%, 4) acidic lipoglucan consisting of 6-O-methyl-D-glucose, glucose, 3-O-methyl-D-glucose, glyceric acid, and 6-9 moles of lower fatty acid esters, 5) glycogen-like highmolecular glucan, 6) low-molecular mannan and glucan.
社団法人日本薬学会の論文
1981-08-25