覚せい剤メタンフェタミンに含まれる不純物の分析

概要

論文の詳細を見る
Impurities in methamphetamine (MA) synthesized from ephedrine were identified by thin-layer chromatography, gas liquid chromatography, infrared spectroscopy, ultraviolet spectroscopy, proton magnetic resonance spectroscopy, gas chromatography/mass spectrometry and neutron activation analysis. Benzyl methyl ketone and iodine were detected as impurities in MA prepared by reducing ephedrine with hydrogen iodide and red phosphorus. Ephedrine, 1-phenyl-2-methylamino-1-propanone, palladium and barium were detected as impurities in MA prepared by reducing ephedrine with hydrogen and Pd-BaSO_4. Ephedrine, 1,2-dimethyl-3-phenyl aziridine, palladium and barium were detected as impurities in MA prepared by reducing chloroephedrine with hydrogen and Pd-BaSO_4. Knowledge of impurities contained in MA provides important information regarding synthetic methods. Impurities contained in seized MA were analyzed by the method described above, and synthetic methods were assumed.
社団法人日本薬学会の論文
1983-12-31