POTENTIATION OF ANTITUMOR ACTIVITY OF 5-FLUORO-2', DEOXYURIDINE BY GUANOSINE-5'-MONOPHOSPHATE
スポンサーリンク
概要
- 論文の詳細を見る
The antitumor activity of 5-fluoro-2'-deoxyuridne (FUdR) against P388 leukemia was markedly enhanced by addition of guanosine-5'-monophosphate (GMP). With daily i.p. treatment for 5 d, the combination of FUdR at 100 mg/kg/d and GMP at 30O mg/kg/d showed the highest antitumor effect (more than 290% ILS), while maximum ILS of FUdR alone (100 mg/kg/d) was 94%.
- 社団法人日本薬学会の論文
著者
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Hoshi Akio
Pharmacology Division National Cancer Center Research Institute
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Iigo Masaaki
Pharmacology Division National Cancer Center Research Institute
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Hoshi Akio
Pharmaceutical Development Laboratories Meiji Seika Kaisha Ltd. : Central Research Laboratories Meij
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IIGO MASAAKI
Pharmacology Division, National Cancer Center Research Institute
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