Bicyclo[3.2.1]octane and 6-Oxabicyclo[3.2.2]nonane Type Neolignans form Magnolia denudata
スポンサーリンク
概要
- 論文の詳細を見る
From the ethyl acetate soluble fraction of twigs of Magnolia denudata (Magnoliaceae), seven new neolignan derivatives, 1-7,were isolated along with eighteen known lignan and neolignan derivatives, 8-25. The structures of the new neolignans were elucidated by means of spectral methods, especially by ^1H-NMR and ^<13>C-NMR spectra, and two dimensional NMR methods such as ^1H-detected heteronuculear multiple bond connectivity(HMBC), ^1H-detected multiple quantum coherence (HMQC) and ^1H-^1H-correlation spectroscopy (COSY). Compounds 1-4 have novel structures possessing a 6-oxabicyclo[3.2.2]nonane skeleton and compounds 5-8 also have novel structures possessing a bicyclo[3.2.1]octane skeleton. The anti-platelet-activating factor (PAF) activity of these compounds was tested by measurement of inhibition activity against acetyl transferase to/lyso-PAF.
- 2000-06-01
著者
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Kuroyanagi Masanori
School Of Bioresources Hiroshima Prefectural University
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Miwa M
Univ. Shizuoka Shizuoka Jpn
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YOSHIDA Kenichi
School of Pharmaceutical Sciences, University of Shizuoka
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YAMAMOTO Atsushi
School of Pharmaceutical Sciences, University of Shizuoka
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MiWA Masao
School of Pharmaceutical Sciences, University of Shizuoka
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Yoshida Kenichi
School Of Pharmaceutical Sciences University Of Shizuoka
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Yamamoto Atsushi
School Of Pharmaceutical Sciences University Of Shizuoka
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