Isolation and Characterization of Seven Lyso Platelet-Activating Factors and Two Lyso Phosphatidylcholines from the Crude Drug "Suitetsu" (the Leech, Hirudo nipponica)

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概要

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• Nine lyso glycerophospholipids were isolated in the pure state from the crude drug "Suitetsu", which is the dried body of the leech, Hirudo nipponica (Hirudidae). They were identified as 1-O-hexadecyl-(1), 1-O-octadecyl-(2), 1-O-tetradecyl-(3), 1-O-9-cis-hexadecenyl-(4), 1-O-hexadecanoyl-(5), 1-O-pentadecyl-(6), 1-O-15-methylhexadecyl-(7), 1-O-octadecanoyl-(8) and 1-O-heptadecyl-sn-glycero-3-phosphocholine (9). Two of them (5 and 8) are lysophos-phatidylcholines and the other seven are lyso platelet-activating factors. One of them has an alkenyl carbon chain.

• 社団法人日本薬学会の論文
• 1993-08-15

著者

• 宮原 一元

  Faculty of Pharmaceutical Sciences, Setsunan University

• 西 正敏

  摂南大・薬

• 西 正敏

  Faculty of Pharmaceutical Sciences, Setsunan University

• 野田 直希

  Faculty Of Pharmaceutical Sciences Setsunan University

• Noda N

  Faculty Of Pharmaceutical Sciences Setsunan University

• 田中 龍一郎

  Faculty of Pharmaceutical Sciences, Setsunan University

• 井上 昌之

  Faculty of Pharmaceutical Sciences, Setsunan University

• 野田 直希

  Faculty Of Pharmaceutical Sciences Kyushu University

• 宮原 一元

  Faculty Of Pharmaceutical Sciences Setsunan University

• 西 正敏

  Faculty Of Pharmaceutical Sciences Setsunan University

• 井上 昌之

  Faculty Of Pharmaceutical Sciences Setsunan University

• Tanaka R

  Osaka Univ. Pharmaceutical Sci. Osaka Jpn

• 田中 龍一郎

  Faculty Of Pharmaceutical Sciences Fukuoka University

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