5-Fluorouracil Derivatives XX. : Synthesis and Antitumor Activity of 5'-O-Unsaturated Acyl-5-fluorouridines
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概要
- 論文の詳細を見る
Various kinds of 5'-O-unsaturated acyl 5-fluorouridines were synthesized to obtain 5-fluorouridine derivatives with low toxicity and high antitumor activity. Antitumor activity of the compounds against L-1210 leukemia in mice was examined, and the 5'-O-4-opentenoyl derivative showed the highest antitumor activity.
- 社団法人日本薬学会の論文
- 1990-11-25
著者
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星 昭夫
National Cancer Center Research Institute
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上原 宣昭
National Cancer Center Research Institute
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尾崎 庄一郎
愛媛大工
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秋山 隆彦
愛媛大工
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尾崎 庄一郎
Department of Resources Chemistry, Faculty of Engineering, Ehime University
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秋山 隆彦
Department of Resources Chemistry, Faculty of Engineering, Ehime University
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森田 剛夫
Department of Resources Chemistry, Faculty of Engineering, Ehime University
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久米川 昌浩
Department of Resources Chemistry, Faculty of Engineering, Ehime University
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長瀬 敏夫
Department of Resources Chemistry, Faculty of Engineering, Ehime University
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上原 宣昭
Chemotherapy, National Cancer Center Research Institute
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上原 宣昭
Chemotherapy National Cancer Center Research Institute
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森田 剛夫
Department Of Resources Chemistry Faculty Of Engineering Ehime University
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長瀬 敏夫
Department Of Resources Chemistry Faculty Of Engineering Ehime University
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久米川 昌浩
Department Of Resources Chemistry Faculty Of Engineering Ehime University
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