Asymmetric Synthesis of 2-Substituted-3-aminocarbonyl Propionic Acid

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An asymmetric synthetic route to 2-substituted-3-aminocarbonyl propionic acid, which is the significant component of low-molecular-weight renin inhibitors, is described. The key step of this synthesis is diastereoselective alkylation by using chiral oxazolidinone and benzyl bromoacetate.
社団法人日本薬学会の論文
1989-08-25

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Asymmetric Synthesis of 2-Substituted-3-aminocarbonyl Propionic Acid

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