Synthese des Dihydro-6,11 5H-pyrimidino[4,5-a]carbazoles et de 11H-Pyrimidino[4,5-a]carbazoles

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概要

• 論文の詳細を見る

• The synthesis of 6,11-dihydro-5H-pyrimidino[4,5-a]carbazoles (10) was achieved by cyclization of 1,2,3,4-tetrahydrocarbazol-1-ones with triformamidomethene. The oxidation with potassium permenganate or mangenese bioxide of 6,11-dihydro-5H-pyrimidino[4,5-a]carbazoles gave the 11 H-pyrimidino[4,5-a]carbazoles (11). The reactions of the pyrimidinocarbazole (11a) with organolithium compounds afforded 4-substituted derivatives (20,21). The structure of the derivatives was determined by proton nuclear magnetic resonance.

• 公益社団法人日本薬学会の論文
• 1989-06-25

著者

• Lancelot Jean-charles

  Laboratoire De Chimie Therapeutique

• Lancelot Jea.charles

  フランス

• Lancelot J‐c

  Centre D'etudes Et De Recherche Sur Le Medicament De Normandie (c.e.r.m.n.) Ufr Des Sciences Ph

• Rault Sylvain

  Laboratoire de Chimie Therapeutique, U.E.R. des Sciences Pharmaceutiques

• Robba Max

  Laboratoire de Chimie Therapeutique, U.E.R. des Sciences Pharmaceutiques

• GAZENGEL JEAN-MARIE

  Laboratoire de Chimie Therapeutique U.E.R. des Sciences Pharmaceutiques, Universite de Caen

• Robba M

  Centre D'etudes Et De Recherche Sur Le Medicament De Normandie Laboratoire De Pharmacochimie Uf

• Robba Max

  Laboratoire De Chimie Therapeutique U.e.r. Des Sciences Pharmaceutiques Universite De Caen

• Rault Sylvain

  C.e.r.m.n. Ufr. Des Sciences Pharmaceutiques

• Lancelot Jean-charles

  Laboratoire De Chimie Therapeutique U.e.r. Des Sciences Pharmaceutiques Universite De Caen

• Gazengel Jean-marie

  Laboratoire De Chimie Therapeutique U. F. R. Des Sciences Pharmaceutiques Universite De Caen

関連論文

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