Un Agent Trichomonacide: Le (Thenoyl-2')-amino-2 nitro-5 thiazole C_8H_5O_3N_3S_2. II. Structure Cristalline et Moleculaire d'une Nouvelle Variete Monoclinique Solvatee par le Dimethylformamide(Medicinal Chemistry,Chemical)

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概要

• 論文の詳細を見る

• C_8H_5O_3N_2S_2・C_3H_7NO crystallizes in dimethylformamide as space group P2_1/n with lattice parameters a=10.370(3), b=8.180(8), c=17.90(1)Å, β=104.30(4)°, V=147lÅ^3, Z=4, D_m=1.56(2), D_x=1.70Mg・m^<-3>. X-Ray data were collected on an ENRAF-NONIUS CAD-4 dif- fractometer using MoKα radiation. The crystal structure was solved by direct methods and refined by full matrix least-squares analysis to a final R of 0.049 for 1783 independent reflections. The molecular geometry does not exhibit significant differences between the type I crystal previously described(without the dimethylformamide molecule as solvate) and the type II now studied. The crystal packing is reinforced by N-H・・・O hydrogen bonding of the amidic group and the DMF molecule. However, in the crystals of type II, the overlapping between adjacent molecules is not observed, contrary to the crystals of type I.

• 公益社団法人日本薬学会の論文
• 1987-06-25

著者

• Lancelot Jean-charles

  Laboratoire De Chimie Therapeutique

• Lancelot Jea.charles

  フランス

• Dung Nguyen

  Laboratoire De Chimie Minerale Et Structurale

• Dung Nguyenhuy

  Laboratoire De Chimie Minerale Et Structurale

• Dung N

  Univ. Caen Caen Fra

• Dung Nguyen

  Laboratoire De Chimie Minerale Et Structurale U.e.r. Des Sciences Pharmaceutiques

• Lancelot J‐c

  Centre D'etudes Et De Recherche Sur Le Medicament De Normandie (c.e.r.m.n.) Ufr Des Sciences Ph

• Robba Max

  Laboratoire de Chimie Therapeutique, U.E.R. des Sciences Pharmaceutiques

• VIOSSAT BERNARD

  Laboratoire de Chimie Generate, U.E.R. de Medicine et Pharmacite

• DUNG NGUYEN-HUY

  Laboratoire de Chimie Minerale et Structurale, U.E.R. des Sciences Pharmaceutiques

• ROBERT FRANCIS

  Chimie des Metaux de Transition et Laboratoire de VA 419, Universite P. et M. Curie

• Robba M

  Centre D'etudes Et De Recherche Sur Le Medicament De Normandie Laboratoire De Pharmacochimie Uf

• Robba Max

  Laboratoire De Chimie Therapeutique U.e.r. Des Sciences Pharmaceutiques Universite De Caen

• Viossat Bernard

  Laboratoire De Chimie Generale

• Lancelot Jean-charles

  Laboratoire De Chimie Therapeutique U.e.r. Des Sciences Pharmaceutiques Universite De Caen

• Robert Francis

  Chimie Des Metaux De Transition Et Laboratoire De Va 419 Universite P. Et M. Curie

関連論文

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• Un Agent Trichomonacide: Le (Thenoyl-2')-amino-2 nitro-5 thiazole C_8H_5O_3N_3S_2. II. Structure Cristalline et Moleculaire d'une Nouvelle Variete Monoclinique Solvatee par le Dimethylformamide(Medicinal Chemistry,Chemical)
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• Synthese de (Pyrrolyl-1)-8 triazolo-1,2,4 [4,3-a] pyridines
• Synthese de Methyl-2 pyrido [3,2-e] pyrrolo [1,2-a] pyrazines
• Dihydro-5,6 oxo-6 pyrido [2,3-e] pyrrolo [1,2-a] pyrazine et Dihydro-5,6 oxo-6 pyrazino [2,3-e] pyrrolo [1,2-a] pyrazine
• Pyrido [3,2-e] pyrrolo [1,2-a] pyrazines
• Synthesis and Preliminary Biological Evaluation of a New Pyridocarbazole Derivative Covalently Linked to a Thymidine Nucleoside as a Potential Targeted Antitumoral Agent. I
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• Cerebral Antihypoxic Activity of New Thienyldihydropyridines
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• Imidazo [4,5-c] carbazoles : Synthese et Etude des Spectres de Resonance Magnetique Nucleaire
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