Un Agent Trichomonacide : le (Thenoyl-2')-amino-2 nitro-5 thiazole. C_8H_5O_3N_3S_2. I-Structure Cristalline et Moleculaire de la Variete Monoclinique

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概要

• 論文の詳細を見る

• C_8H_5O_3N_3S_2 crystallizes in space group P2_1/c with D_m=1.56 (2) in a mixture of dimethyl-formamide and methyl ethyl ketone. On the other hand, in acetone, the title compound crystallizes in space group C2/c with lattice parameters a-25.66 (4), b=7.360 (5), c=11.05 (8)Å, β=105.0 (3)°; Z=8; D_m=1.70 (2), D_x=1.68Mg・m^<-3>. The molecular structure was investigated by X-ray diffraction analysis of a single crystal; the final R value was 0.04 for 1823 reflections. The molecules related by a center of symmetry lie one above the other along the b axis and these stacks are linked by intermolecular hydrogen bonding between N-H…N of the amidic group and the thiazole ring, respectively.

• 公益社団法人日本薬学会の論文
• 1986-03-25

著者

• Lancelot Jean-charles

  Laboratoire De Chimie Therapeutique

• Lancelot Jea.charles

  フランス

• Dung Nguyen

  Laboratoire De Chimie Minerale Et Structurale

• Dung Nguyenhuy

  Laboratoire De Chimie Minerale Et Structurale

• Dung Nguyen

  Laboratoire De Chimie Minerale Et Structurale U.e.r. Des Sciences Pharmaceutiques

• Lancelot J‐c

  Centre D'etudes Et De Recherche Sur Le Medicament De Normandie (c.e.r.m.n.) Ufr Des Sciences Ph

• VIOSSAT BERNARD

  U.E.R. des Sciences Pharmaceutiques, 1, rue Vaudenard, Laboratoire de Chimie Generale

• LANCELOT JEAN-CHARLES

  U.E.R. de Medecine et Pharmacie, 34, rue du Jardin des Plantes, France et Laboratoire de Chimie Ther

• ROBBA MAX

  U.E.R. des Sciences Pharmaceutiques, 1, rue Vaubenard

• Dung Nguyen

  Laboratoire De Cbimie Minerale Et Structurale

• Robba M

  Centre D'etudes Et De Recherche Sur Le Medicament De Normandie Laboratoire De Pharmacochimie Uf

• Viossat Bernard

  Laboratoire De Chimie Generale

• Lancelot Jean-charles

  Laboratoire De Chimie Therapeutique U.e.r. Des Sciences Pharmaceutiques Universite De Caen

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