Reaction of 6-Substituted 1,3-Dimethyluracils with Benzoyl Peroxide

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概要

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• The reaction of 6-hydrazino-1,3-dimethyluracil (II) with the benzoyloxy radical gave a tricyclic pyridazine derivative, 1,3,6,8-tetramethyl-2,4,5,7-tetraoxo-1,2,3,4,5,6,7,8-octahydropyridazino [3,4-d : 6,5-d'] dipyrimidine (VII), while the reaction of 6-amino-1,3-dimethyluracil (I) with the benzoyloxy radical afforded 6-amino-5-benzoyloxy-1,3-dimethyluracil (VI). Treatment of VII with ammonia gave another tricyclic pyridazine derivative, 2,4,7,9-tetramethyl-1,3,8-trioxo-1,2,3,4,7,8,9-heptahydropyrimido [4,5-c] imidazo [4,5-e] pyridazine (VIII).

• 社団法人日本薬学会の論文
• 1979-09-25

著者

• 高田 純

  北里大(薬)

• 倉沢 嘉久

  School of Pharmaceutical Sciences, Kitasato University

• 高田 純

  School of Pharmaceutical Sciences, Kitasato University

• 長原 勝彦

  School of Pharmaceutical Sciences, Kitasato University

• 長原 勝彦

  Faculte Des Sciences Pharmaceutiques Universite Kitasato

• 高田 純

  School Of Pharmaceutical Science Kitasato University

• 倉沢 嘉久

  School Of Pharmaceutical Sciences Kitasato University

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