Researches on Chemotherapeutic Drugs against Viruses. XXXIII. Syntheses and Antiviral Activity of 1-Phenyl-3-amino-1-propanol Derivatives.
スポンサーリンク
概要
- 論文の詳細を見る
Eight compounds of 1-(p-alkylphenyl)-1-phenyl-3-(1-piperidyl)-1-propanol series, seven compounds of 1-(p-alkylphenyl)-1-phenyl-3-dimethylamino-1-propanol series, five compounds of 3-(1-piperidyl)-4'-alkylthiopropiophenone series, four compounds of 1-(p-alkylthiophenyl)-1-phenyl-3-(1-piperidyl)-1-propanol series, and seven compounds of 1-alkyl-1-(p-alkylphenyl)-3-(1-piperidyl)-1-propanol series were synthesized and their antiviral activities were tested. Several compounds of these series were found to be effective on the PR-8 strain of influenza A virus in chorioallantoic membrane, especially, 3-(1-piperidyl)-4'-octylthiopropiophenone and 1-cyclohexyl-1-(p-tolyl)-3-(1-piperidyl)-1-propanol. Several compounds of these series showed in vivo effect on the Nakayama strain of Japanese B encephalitis virus.
- 公益社団法人日本薬学会の論文
- 1961-11-25
著者
関連論文
- Color Reaction of Cholesterol with Benzoyl Peroxide in Concentrated Trichloroacetic Acid
- Tautomeric Character of 3-Heteroarylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxalines
- Synthesis and Reactions of 3-(1,2,4-Triazol-5-yl) methylene-2-oxo-1,2,3,4-tetrahydroquinoxalines
- Revised Structure for the Product from the Reaction of 3-Hydrazinocarbonylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline with Nitrous Acid
- Facile Synthesis and Ring Transformations of a Spiro-[cyclobutene-1,2'(1H)-quinoxaline]
- Synthesis and Reactions of 3-(1,3,4-Oxadiazol-2-yl) methylene-2-oxo-1,2,3,4-tetrahydroquinoxalines
- Halogenations of 3-Methoxycarbonylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline
- Preparation and Ring Conversion of Furo [2,3-b] quinoxaline
- Synthesis of 4-Substituted 1,2-Dihydropyridazino [3,4-b] quinoxalines from 3-(N, N-Dimethylaminocarbonyl) furo [2,3-b] quinoxaline
- A Convenient Synthesis of Pyridazino [4,5-b] quinolines and Pyrrolo [3,4-b] quinolines
- Reaction of 6-Substituted 1,3-Dimethyluracils with Benzoyl Peroxide
- Dimeric Steroid Formation in the Color Reaction of Cholesterol
- Color Reaction of Estrone with the Antimony Trichloride Reagent
- Color Reaction of Cholesterol in Concentrated Trichloroacetic Acid Media
- Reaction of Ethoxymethylenemalononitrile with 2-Aminopyridines
- The Reaction of Ethyl ω-Haloalkylimidate Hydrochloride with 2-Aminoheterocycles
- Reaction of Ethyl 3-Chloropropionimidate with Aminoheterocycles
- Synthesis of 3,3'-Biquinazoline-4,4'-diones and 1,3,4-Oxadiazoles from Isatoic Anhydride
- Color Reaction of Cholesterol with the Antimony Trichloride Reagent
- Reaction of Triethyloxonium Fluoroborate with Acid Amide. III. Formation of Quinazoline and 4H-3,1-Benzoxazin-4-one Derivatives
- Color Reaction of Aromatic Aldehydes with Acenaphthene in Concentrated Sulfuric Acid
- Reaction of Triethyloxonium Fluoroborate with Acid Amide. I. Formation of Cyclic Amidine and Tetrahydropyrimidine
- Researches on Chemotherapeutic Drugs against Viruses. XXXIV. Syntheses and Antiviral Activity of 10-(ω-Dialkylaminoalkyl)-alkylphenothiazine and N-Substituted 10-Glycyl-alkylphenothiazine.
- Researches on Chemotherapeutic Drugs against Viruses. XXXIII. Syntheses and Antiviral Activity of 1-Phenyl-3-amino-1-propanol Derivatives.
- Researches on Chemotherapeutic Drugs against Viruses. XXVIII. Synthesis and Antiviral Effect of 1-(p-Alkylphenyl)-1-phenyl-2-methylamino-1-propanol