Modification of Drug-Metabolizing Enzyme Activity of Rats in Carrageenin-Inflammation
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概要
- 論文の詳細を見る
The activity of drug-metabolizing enzymes in hepatic microsomes of rats with inflammatory lesions was determined. In the Donryu-rats carrying carrageenin-induced granuloma, the cytochrome P-450 and b_5 levels and the activity of aniline hydroxylase in hepatic microsomes were depressed markedly at day 6 after s. c. injection of carrageenin when the granuloma formation and exudate accumulation occur rapidly. However, at day 15 after carrageenin injection when the granuloma is in regression, the activity of these enzymes was decreased slightly but without significant differences.
- 公益社団法人日本薬学会の論文
- 1977-11-25
著者
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高畠 英伍
Department of Toxicology, Faculty of Pharmaceutical Sciences, Setsunan University
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高畠 英伍
Department Of Toxicology Faculty Of Pharmaceutical Sciences Setsunan University
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福原 守雄
The Institute of Public Health
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高畠 英伍
The Institute of Pubic Health
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福原 守雄
Department Of Pharmaceutical Sciences National Institute Of Public Health
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Takabatake E
Department Of Toxicology Faculty Of Pharmaceutical Sciences Setsunan University
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