Investigations on Pantothenic Acid and Its Related Compounds. XIII. Chemical Studies. (6). Syntheses of Homopantethine and Some Other Pantethine Analogs

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概要

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• Four pantethine analogs (homopantethine (VII), α-methyl-(XIIIb) and β-methyl-pantethine (XIIIc), and oxypantetheine (XVI)) were prepared. Synthesis of VII from D-pantothenonitrile (I) and homocysteamine by using the thiazine derivative (III) as an intermediate was established. XIIIb and XIIIc were synthesized by the thiazoline method described previously, and XVI by the general method.

• 公益社団法人日本薬学会の論文
• 1968-06-25

著者

• 清水 正夫

  Central Research Laboratory, Daiichi Seiyaku Co., Ltd.

• 長瀬 脩

  Research Institute Daiichi Seiyaku Co. Ltd.

• 長瀬 脩

  Central Research Laboratory, Daiiohi Seiyaku Co., Ltd.

• 田川 博昭

  Central Research Laboratory, Daiichi Seiyaku Co., Ltd.

• 清水 正夫

  Central Research Laboratory Daiichi Seiyaku Co. Ltd.

• 田川 博昭

  Research Laboratories Daiichi Seiyaku Co. Ltd.

• 長瀬 脩

  Research Laboratories Daiichi Seiyaku Co. Ltd.

• 長瀬 脩

  Central Research Laboratory, Daiichi Seiyaku Co., Ltd.

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