Studies on Cinnolines. IV. ON Nitration of Cinnoline 2-Oxide
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概要
- 論文の詳細を見る
Cinnoline 2-oxide (I) gave 5-, 6-and 8-nitrocinnoline 2-oxides (II, III, and IV) on warming with nitric and sulfuric acids or potassium nitrate in sulfuric acid. The nitration of I with benzoyl nitrate afforded II. 5-, 6- and 8-Aminocinnolines (V, VI, VII), 6-and 8-aminocinnoline 2-oxides (VIII and IX), and 5-aminodihydrocinnoline (X) were synthesized for the determination of the structures of II, III and IV. The effect of 2-N-oxide of I in this reaction was affected by the concentration of sulfuric acid and the reaction temperature.
- 公益社団法人日本薬学会の論文
- 1966-08-25
著者
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鈴木 郁生
国立衛生試験所
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鈴木 郁生
National Hygienic Laboratory
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中島 利章
Central Research Laboratories, SS Pharmaceutical Co., Ltd.,
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中島 利章
National Institute of Hygienic Sciences
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長沢 奈都子
National Institute of Hygienic Sciences
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中島 利章
Central Research Laboratory Ss Pharmaceutical Co. Ltd.
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