Studies on Food Additives. VI. Metabolism of 2,6-Di-tert-butyl-p-cresol (BHT) in a Rabbit. (1). Determination and Paper Chromatography of a Metabolite.
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概要
- 論文の詳細を見る
Metabolism of the antioxidant, 2,6-di-tert-butyl-p-cresol (BHT), was studied in a rabbit. After administration of 0.5g./kg. of BHT by mouth, 37.5% of it was excreted as glucuronides, 16.7% as ethereal sulfates, and 6.8% as free phenols. α-Hydroxy-2,6-di-tert-butyl-p-cresol, 3,5-di-tert-butyl-4-hydroxybenzoic acid and 4,4'-ethylenebis (2,6-di-tert-butylphenol) were identified by paper chromatography from the rabbit urine 24 hours after the administration of 0.5g./kg. of BHT. Unchanged BHT was isolated from the feces, but not from the urine.
- 公益社団法人日本薬学会の論文
- 1962-02-25
著者
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青木 勇
Faculty Of Pharmaceutical Sciences Hokkaido University
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赤木 満洲雄
Faculty of Pharmaceutical Sciences, School of Medicine, Hokkaido University
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赤木 満洲雄
Faculty Of Pharmaceutical Sciences Hokkaido University
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