Studies on the Constituents of Digitalis purpurea L. XI. Digifucocellobioside, a New Cardiotonic Glycoside from Digitalis Seeds.
スポンサーリンク
概要
- 論文の詳細を見る
The structure of substance C-II, newly isolated by the writers and described in the preceding paper, was examined. This substance occurs as a crystalline powder, m.p. 238〜242°(Kofler, uncorr.), C_<41>H_<64>O_<18>・2H_2O ; [α]^<20>_D-1.4° ; U.V. λ^<EtOH>_<max> 218 mμ (log ε 4.22). The sugar portion obtained by hydrolysis of Kiliani method was identified as fucose and glucose on paper chromatography. The partial decomposition of substance C-II afforded glucodigifucoside (digitoxigenin β-D-glucosido-β-D-fucoside), by elimination of one mole of glucose. The acetolysis of the acetate of substance C-II gave α-octaacetylcellobiose and it was established that substance C-II is digitoxigenin β-cellobiosido-β-D-fucoside. This is a new cardioglycoside and was named digifucocellobioside.
- 公益社団法人日本薬学会の論文
- 1959-03-20
著者
-
岡野 淳二
Central Research Laboratory Daiichi Seiyaku Co. Ltd.
-
三木 藤作
Exploratory Research Laboratories III, Daiichi Pharmaceutical Co., Ltd.,
-
岡野 淳二
Research Laboratory, Daiichi Seiyaku Co., Ltd.
-
傍士 和彦
Research Laboratory, Daiichi Seiyaku Co., Ltd.
-
三木 藤作
Research Laboratory, Daiichi Seiyaku Co., Ltd.
-
坂下 昭夫
Research Laboratory, Daiichi Seiyaku Co., Ltd.
-
三木 藤作
Exploratory Research Laboratories Iii Daiichi Pharmaceutical Co. Ltd.
-
傍士 和彦
第一製薬株式会社
-
坂下 昭夫
Research Laboratory Daiichi Seiyaku Co. Ltd.
関連論文
- Syntheses of 2-(3,4-Dimethoxyphenyl)ethylamine Derivatives and Their Antiulcer Activities
- Medicinal Chemical Studies on Antiplasmin Drugs. II. Separation of Stereoisomers of 4-Aminomethylcyclohexanecarboxylic Acid and Assignment of Their Configuration
- Medicinal Chemical Studies on Antiplasmin Drugs. I. Establishment of the Screening Assay Method for Antiplasmin Drugs and the Superiority of trans-4-Aminomethylcyclohexanecarboxylic Acid (Tranexamic Acid) to cis-Form
- trans-4-Aminomethylcyclohexanecarboxylic Acid as a Potent Antiplasmin Agent
- Studies on the Constituents of Digitalis purpurea L. XXIII. On the 16-Formyl Derivative of Digitalinum Verum.
- Studies on the Constituents of Digitalis purpurea L. XXII. Alloneogitostin, a New Glycoside from Digitalis Seeds.
- Studies on the Constituents of Digitalis purpurea L. XXI. Allo-digitalinum verum, a New Glycoside from Digitalis Seeds.
- Studies on the Constituents of Digitalis purpurea L. XVII. Isolation of Several New Glycosides from Fraction PGB of Digitalis Seeds.
- 16-Acetylgitoxin, a New Derivative of Gitoxin
- Studies on the Constituents of Digitalis pur purea L. XVI. : On the Synthesis of 16-Acetyl-strospeside.
- Studies on the Constituents of Digitalis purpurea L. XIV. 16-Acetyl and 16-Propionyl Derivatives of Digitalinum Verum.
- Studies on the Constituents of Digitalis purpurea L. XIII. On the Diacyl Derivatives of Digitalinum Verum.
- Studies on the Constituents of Digitalis purpurea L. XII. New Cardiotonic Glycosides, Gitorocellobioside, Glucogitoroside, and Gitoxin-cellobioside.
- Studies on the Constituents of Digitalis purpurea L. XI. Digifucocellobioside, a New Cardiotonic Glycoside from Digitalis Seeds.
- Studies on the Constitutents of Digitalis purpurea L. X. Isolation of Several New Glycosides from the Water-soluble Fraction of Digitalis Seeds.
- Studies on the Constituents of Digitalis purpurea L. IX. The Structures of Gitostin and Neogitostin.
- Studies on the Constituents of Digitalis purpurea L. VIII. The Isolation of Neogitostin, a New Cardiotonic Glycoside.
- 9.ジギタリスの新強心配糖体
- Studies on the Constituents of Digitalis purpurea L. V. On the Acetates of Some Cardiotonic Glycosides.
- Studies on the Constituents of Digitalis purpurea L. IV. Enzymatic Decomposition of Gitostin.
- Studies on the Constituents of Digitalis purpurea L. III. Gitostin, a New Cardiotonic Glycoside from Digitalis Seeds.
- Studies on the Constituents of Digitalis purpurea L. II. Paper Partition Chromatography of Cardioglycosides from Digitalis Seeds.
- Medicinal Chemical Studies on Antiplasmin Drugs. VI. Aza Analogs of 4-Aminomethylbenzoic Acid
- カタツムリCepaea hortensisによるスルファモノメトキシンの酸化とアセチル化
- カタツムリCepaea hortensisによるスルファモメトキシンのO-脱メチル化とN_4-アセチル化
- Studies on the Constituents of Digitalis purpurea L. XXVI. Purpurea Glycoside-A and Purpurea Glycoside-B from Digitalis Seeds.
- Studies on the Constituents of Digitalis purpurea L. XXV. A New Cardiotonic Glycoside, Acetylglucogitoroside and Digitalinum verum Monoacetate from Digitalis Seeds.
- Studies on the Constituents of Digitalis purpurea L. XXIV. On the Structures of Purlanosides-A and -B.
- Studies on the Constituents of Digitalis purpurea L. XX. New Cardiotonic Glycosides, Acetyl-digitoxin-γ and Acetyl-gitoxin-γ.
- Studies on the Constituents of Digitalis purpurea L. XIX. New Cardiotonic Glycosides, Purlanoside-A and Purlanoside-B from Digitalis Seeds.
- Studies on the Constituents of Digitalis purpurea L. XVIII. Odorobioside-G from Digitalis Seeds.