Technetium-99m Complexes with Steroid-2-aminooxyethyliminodiacetic Acid Conjugates
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概要
- 論文の詳細を見る
Conjugates of 2-aminooxyethyliminodiacetic acid with estrone, testosterone, epiandrosterone, 17-α-hydroxy-progesterone and progesterone were synthesized and their complexes with Tc-99m were successfully prepared in good yields, which indicated the agent to be promising for metal-labeling of biomolecules and related substances containing one or more carbonyl groups. The biodistribution and scintigraphic studies in mice bearing Ehrlich tumor and mammary tumor showed that the radioactivity accumulated considerably in the tumor tissues, but the tumor images were somewhat obscured.
- 公益社団法人日本薬学会の論文
- 1999-03-15
著者
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Takata Jiro
Laboratory Of Drug Design And Drug Delivery Faculty Of Pharmaceutical Sciences Fukuoka University
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MATSUSHIMA Yoshikazu
Kyoritsu College of Pharmacy
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NAGATA Yoshiko
Kyoritsu College of Pharmacy
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Karube Yoshiharu
Faculty Of Pharmaceutical Sciences Fukuoka University
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YOSHIDA Keisuke
Faculty of Pharmaceutical Sciences, Fukuoka University
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Yoda R
Kyoritsu College Of Pharmacy
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Takata Jiro
Faculty Of Pharmaceutical Sciences Fukuoka University
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Matsuoka Yuji
School Of Medicine Fukuoka University
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Nagata Y
Kyoritsu College Of Pharmacy
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Matsushima Y
Kyoritsu College Of Pharmacy
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YODA Reiko
Kyoritsu College of Pharmacy
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