Oxidation of d-α-Tocopherol in Aqueous Solution. Formation of Colored Products
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概要
- 論文の詳細を見る
An aqueous solution of d-α-tocopherol solubilized with sodium deoxycholate became colored on standing, probably due to air oxidation. 5-Formyl-7,8-dimethyltocol (1) and 7-formyl-5,8-dimethyltocol (2) were isolated from the solution and concluded to be responsible for the coloration. In oxidation of aqueous solutions of d-α-to-copherol, the time course of formation of products was followed by analytical HPLC. The main oxidation product was 1 in solutions solubilized with sodium deoxycholate and sodium cholate, whereas α-tocoquinone was the main product in those solubilized with 2,6-di-O-methyl-β-cyclodextrin.
- 公益社団法人日本薬学会の論文
- 1999-07-15
著者
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MATSUMOTO Shigenobu
Tokyo Metropolitan Institute of Gerontology
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Matsumoto Shun-ichiro
Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.
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MATSUSHIMA Yoshikazu
Kyoritsu College of Pharmacy
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NAGATA Yoshiko
Kyoritsu College of Pharmacy
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Matsumoto Sayaka
Faculty Of Pharmaceutical Sciences Osaka University
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Matsuoka Yuji
School Of Medicine Fukuoka University
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Nagata Y
Kyoritsu College Of Pharmacy
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Matsushima Y
Kyoritsu College Of Pharmacy
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Miyamoto C
Kyoritsu College Of Pharmacy
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MIYAMOTO Chie
Kyoritsu College of Pharmacy
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