LDL吸着療法の臨床応用 : 腎疾患と下肢閉塞動脈硬化症

概要

論文の詳細を見る
Since the LDL aphresis treatment has been applied to patients with familial hyperlipidemia with coronary arteriosclerosis, this method has been ssed to treat many diseases due to hyperlipidemia. In this paper we reviewed the reports of renal disease, especially FGS treated with LDL aphresis, and discussed the mechanism of the effect. Moreover, we reported the application of LDL apheresis for diabetic nephropathy, chronic renal failure with hyperlipidemia and ASO complications on regular hemodialysis diabetic patients. On diabetic nephropathy, the effect to prevent the retardation of renal function was observed in cases that the serum creatinine level showed below 3.0 mg/dl. LDL aphresis is effective for ASO of diabetic hemodialysis patients. Further investigation is necessary to evaluate the efficacy of LDL aphresis for diabetic nephropathy and ASO of dialysis patients.
日本アフェレシス学会の論文
2000-06-30