ヒトデの卵巣に存在するプロジェステロンについて

概要

論文の詳細を見る
The meiosis-inducing substance of starfish has recently been identified as 1-methyladenine (Kanatani et al., 1969). This substance is produced in the gonad under the influence of a hormonal peptide released from the nirvous system (Kanatani and Shirai, 1967; Schuetz and Biggers, 1967) and acts on the surface of the oocyte to induce maturation (Kanatani and Hiramoto, 1970). On the other hand, progesterone is known to induce oocyte maturation in frog eggs (Masui, 1967; Schuetz, 1967; Smith et al., 1968), and Botticelli et al., (1960) have suggested that this substance is present in starfish gonads. The present study was conducted in order to determine whether progesterone exists in the ovary of Asterias amurensis, where 1-methy ladenine is known to be produced. Using 3,100g of dry ovaries taken from 2,300 females as starting material, the occurence of progesterone was clearly demonstrated by gas chromatography and mass spectroscopy after a purification process consisting of several steps (Fig. 1). When tested on Asterina pectinifera, however, progesterone was found to have no effect in inducing either oocyte maturation (Table 1) or release from the nervous tissue of the gonad-stimulating hormonal peptide which is responsible for spawning and oocyte maturation. The physiological significance of progesterone present in the starfish ovary remains to be elucidated.
社団法人日本動物学会の論文
1971-01-15