モルモット骨髄による誘導効果の時間関係 : II.モルモット肝の継時的接触の影響

概要

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Using two kinds of inductor (guinea pig bone-marrow extract (BM) as a mesodermal inductor and liver extract (L) as a neural one) the modifying action of the latter upon the inductive effect of the former was tested on the ectoderm from newt (Triturus pyrrhogaster) gastrulae at St. 12; the mesodermalizing BM, after 3, 5 and 7 hours, contact with the isolated presumptive ectoderm was replaced by the neuralizing L. The results were examined after 10 days of cultivation by ordinary microscopic technique. The results revealed that (1) after 3 and 5 hours' contact with BM, the course of mesodermal differentiation of the ectoderm was changed into spinocaudal one by subsequent neural effect of the L, and (2) after 7 hours, contact with BM, the ectoderm reached the stationary phase of maximum reaction to the BM effect and did not further react to the action of L.
社団法人日本動物学会の論文
1972-01-15