Effect of Hypoglycemic Stress on the Pars Intermedia of the Mouse Pituitary Gland : An Ultrastructural Analysis
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概要
- 論文の詳細を見る
The present study was made to clarify the relationship between functions of the pars intermedia of the mouse pituitary gland and hypoglycemic stress. Morphometrical analysis of the ultrastructures of the pars intermedia cells showed (1) a rise in the percentage volume of rough endoplasmic reticulum (r-ER) indicative of an increase in protein synthesis, (2) an increase in the number of Golgi granules per unit Golgi area showing an induction of granule-forming activity and (3) a decrease in the numerical density of secretory granules reflecting a release of the secretory granules. These findings suggest that hypoglycemic stress induced by daily treatment with insulin or restriction of food intake was able to elicit heightened secretory activity of the pars intermedia cells of the mouse pituitary gland. However, acute hypoglycemic stress induced by food deprivation did not cytologically affect the pars intermedia. These observations suggest that repeated hypoglycemic stress, rather than acute hypoglycemic stress, may be a natural physiological stimulus of the pars intermedia of the mouse pituitary gland.
- 社団法人日本動物学会の論文
- 1995-02-15
著者
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Takahashi Sumio
Department Of Applied Physics The National Defense Academy
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TAKEUCHI Makoto
Department of Medicine, National Minami Okayama Hospital
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Takeuchi M
Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.
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Takeuchi Makoto
Chemistry Research Laboratories Astellas Pharmaceutical Inc.
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Takeuchi M
Chemistry Research Laboratories Astellas Pharmaceutical Inc.
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Takahashi Sumio
Department Of Applied Physics National Defense Academy
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Takeuchi Makoto
Department Of Earth And Planetary Sciences Graduate School Of Environmental Studies Nagoya Universit
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Takeuchi Makoto
Department Of Dermatology Fujita Health University School Of Medicine
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Takeuchi Makoto
Department Of Biology Faculty Of Science Okayama University
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