DISTRIBUTION OF SULFHYDRYL AND DISULFIDE GROUPS IN OCULAR TISSUES

概要

論文の詳細を見る
The localization and concentration of protein-bound sulfhydryl groups and disulfide linkages in mouse ocular tissues were examined with a new fluorescent thiol reagent, N-(7-dimethylamino-4-methylcoumarinyl)-maleimide (DACM). Corneal epithelium and endothelium, conjunctival epithelium, lens cortex, retinal plexiform layers and inner segment and pigment epithelium were rich in SH groups. Descemet's membrane and lens capsule contained many S-S linkages. Corneal stroma, sclera and retinal outer segment contained a moderate number of S-S linkages. There was a unique distribution of SH groups and S-S linkages in the eye ; that is, tissues abundant in SH groups contained few S-S linkages, and tissues abundant in S-S linkages contained few SH groups. The role of SH groups and S-S linkages in the eye was discussed.
日本組織細胞化学会の論文