Study on Rat Subcutaneous Reaction to Experimental Polyurethane Elastomers

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概要

• 論文の詳細を見る

• The purpose of the study was to investigate the biocompatibility of experimental elastomers, E580 and E590. The experimental elastomers and the control - a clinically used elastomer - were implanted into the subcutaneous tissue of rats. The tissue reactions were examined histologically on the 3rd, 7th, 14th, 28th, and 56th day after implantation. It was found that there were some irritant responses in the tissues adjacent to the implanted elastomers during the first week. However, the inflammatory tissue reaction subsided substantially from the second week onwards. The stable fibrous capsule surrounding the elastomer was formed after eight weeks. The tissue responses of the control, E580, and E590 were similar. The results suggested that the long-term tissue irritation of the experimental elastomers was so low such that they have the potential to be applied clinically.

• 日本歯科理工学会の論文

著者

• MIYAZAKI Koji

  Departments of Surgery, Saga Medical School

• Wang Xing

  Graduate School Department Of Dental Engineering Fukuoka Dental College

• Baba Atsuko

  Department Of Oral Growth & Development Fukuoka Dental College

• Taniguchi Kunihisa

  Department Of Morphological Biology Fukuoka Dental College

• HAGIO Maki

  Department of Oral Growth & Development, Fukuoka Dental College

• Miyazaki Koji

  Department Of Dental Engineering (bioengineering Section) Fukuoka Dental College

• Hagio Maki

  福岡歯科大学 成育小児歯科学

• Miyazaki K

  Department Of Dental Engineering Fukuoka Dental College

• Miyazaki Koji

  Department Of Biological Functions And Engineering Kyushu Institute Of Technology

• Taniguchi Kunihisa

  Department Of Biological Morphology Fukuoka Dental College

• MIYAZAKI Koji

  Department of Applied Chemistry, Tokyo Metropolitan University

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