オルガノゲル担体に固定化したCandida rugosaリパーゼによるエステル合成の反応条件と連続反応

概要

論文の詳細を見る
Gelatin-containing di-2-ethylhexyl sodium sulfosuccinate (AOT) microemulsion-based organogels (MBGs) were investigated as a reaction medium for the esterification of lauric acid with butyl alcohol cat-alyzed by Candida rugosa lipase. The initial reaction rate was maximum at a W_G (=[H_2O]/[AOT] in the MBG phase) value of 100. The MBG particle radius for reaction-controlled operation is examined as a function of the bulk substrate concentration. Immobilized lipase was also used in a continuous reaction using a reactor fitted with a basket-type impeller. The lipase activity was maintained successfully over a period of 36 d by the removal of water that accumulated in the MBGs using a concentrated AOT solution.
社団法人日本生物工学会の論文
2002-03-25