Riboflavin結晶の工業的製造に關する研究(第4報) : Na-hydrosulfite還元法の検討

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Various conditions were examined for the precipitation of reduced riboflavin by adding Nahydrosulphite to the embryo-culture of Eremothecium Ashbyii.In pure riboflavin solution, the mother liquor after the precipitation of reduced riboflavin by adding Na-hydrosulphite contains only about 6 γ/ce of riboflavin, bat in the extract of fungus culture, more riboflavin is left. Riboflavin remaining in mother liquor is almost proportional to the original ribolfavin concentration, ranging 7〜10% of total riboflavin.Optimum pH for riboflavin precipitation is pH 4〜6 and the temperature suitable for the addition of Na-hydrosulphite is below 50°C.Na-hydrosulphite required for the precipitation of reduced riboflavin about 2.5 times of riboflavin contained in the solution.
社団法人日本生物工学会の論文
1949-06-15