女子大学生のビタミンB_<12>, 葉酸栄養状態について : 血清ビタミンB_<12>, 葉酸濃度の分布範囲

概要

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To clarify the vitamin B_<12> (B_<12>) and folate status in young women, serum B_<12> and folate levels were determined in 252 female students aged 21〜22 years, and their dietaly intakes were assessed from a 3-day food record. The serum vitamin levels were measured by chemiluminescence competittiive binding assay using ACS-B12/Folate (Bayer Medical). The mean of serum B_<12> and folate levels, and the lower limit of 95 % confidential interval for serum folate were 10 %, 34 % and 49 % higher by ACS than by Elecsys VB12/Folate (Roch Diagnostics). The energy intake (1633 ± 296 kcal/day) was lower than the RDA, The B_<12> intake was 4.79 ± 3.55 μg/day, and folate intake was 190.6 ± 70.0 μg/day, and 76.7 % and 40.2 % of the students had been fulfilled their RDAs of the former and the latter, respectively A Significant correelation was found only between serum folate level and dieetary intakes. The 2.5〜97.5 % distribution range of serum B_<12> was 300〜1160 (638.0 ± 199.3) pg/ml and that of folate was 4.6〜13.5 (8.34 ± 2.04) ng/ml, which were obtained from the subjects with their vitamin intakes above RDAs.
日本ビタミン学会の論文
2000-06-25