High-cholesterol Diets Induce Changes in Lipid Composition of Rat Erythrocyte Membrane Including Decrease in Cholesterol, Increase in α-Tocopherol and Changes in Fatty Acids of Phospholipids(Food & Nutrition Science)
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概要
- 論文の詳細を見る
Effects of high dietary cholesterol on erythrocyte membrane lipids were studied. Feeding rats with a diet containing 0.5% cholesterol and 0.15% sodium cholate for two weeks induced changes in erythrocyte membrane lipids including a decrease in cholesterol, an increase in α-tocopherol (α-Toc) and changes in the fatty acid composition of phospholipids. Oleic acid and linoleic acid increased, while arachidonic acid decreased in phosphatidylcholine. Saturated fatty acids decreased and unsaturated fatty acids increased in phosphatidylethanolamine. Almost the same changes in membrane lipids were also noted after six weeks of feeding rats with the diet. A diet containing 0.5% cholesterol but without sodium cholate caused a decrease in erythrocyte cholesterol and an increase in erythrocyte α-Toc after two weeks of feeding, as compared to the basal diet, indicating that high dietary cholesterol, but not sodium cholate, was responsible for these changes in the erythrocyte membrane.
- 社団法人日本農芸化学会の論文
- 2003-07-23
著者
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Maruyama Toru
Institute Of Health Science Kyushu University
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Maruyama Toru
九州大学 医学研究院病態修復内科学分野
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Ohnishi Yasushi
First Department Of Internal Medicine Faculty Of Medicine Kyushu University
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Kaji Yoshikazu
Medicine And Biosystemic Science Kyushu University Graduate School Of Medical Sciences
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Kaji Yoshikazu
九州大学 医学研究院病態修復内科学
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Kaji Yoshikazu
Department Of Medicine And Biosystemic Science Kyushu University
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Kaji Yoshikazu
First Department of Internal Medicine, Faculty of Medicine, Kyushu University
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MURAKAMI Kaori
Department of Chemistry, Faculty of Science, Kochi University
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Kanda Yoshinobu
Department Of Hematology And Oncology Graduate School Of Medicine University Of Tokyo
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Kanda Yoshinobu
Department Of Cell Therapy And Transplantation Medicine University Of Tokyo Hospital
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Fujino T
Institute Of Rheological Function Of Foods Co Ltd
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Mawatari S
Department Of Nutrition And Health Science Faculty Of Human Environmental Science Fukuoka Women&apos
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Mawatari Shiro
Department Of Nutrition And Health Science Faculty Of Human Environmental Science Fukuoka Women&apos
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Fujino Takehiko
The Institute Of Rheological Functions Of Food Co. Ltd.
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MARUYAMA Tohru
The Institute of Rheological Functions of Food Co., Ltd.
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TSUTSUI Koichiro
The Institute of Rheological Functions of Food Co., Ltd.
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Maruyama Tohru
Institute Of Health Science Kyushu University
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Tsutsui Koichiro
The Institute Of Rheological Functions Of Food Co. Ltd.
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Kaji Yoshikazu
First Department Of Internal Medicine Faculty Of Medicine Kyushu University
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Murakami Kaori
Department Of Chemistry Faculty Of Science Kochi University
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Maruyama Tohru
The Institute Of Rheological Functions Of Food Co. Ltd.
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Fujino Takehiko
Department Of Physiology Nippon Medical School Tokyo
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Maruyama T
Institute Of Health Science Kyushu University
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Kikushige Yoshikane
Medicine And Biosystemic Science Kyushu University Graduate School Of Medical Sciences
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Murakami Kaori
Department Of Nutrition And Health Science Faculty Of Human Environmental Science Fukuoka Women&apos
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Kaji Yoshikazu
Division Of Hematology Saitama Medical Center Jichi Medical University
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Yamamoto K
Department Of Hematology And Oncology Graduate School Of Medicine University Of Tokyo
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Kaji Yoshikazu
The First Departrnent Of Internal Medicine Kyushu University Fukuoka
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FUJINO Takehiko
The Institute of Health Science, Kyushu University
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MAWATARI Shiro
Department of Neurology, Chikugo National Hospital
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