Enzymes Acting on Peptides Containing D-Amino Acid
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概要
- 論文の詳細を見る
Mainly microorganisms but only a few higher organisms are presently known to express enzymes that hydrolyze peptides containing _D-amino acids. These enzymes can be involved in proceedings at the bacterial cell wall, in either assembly or modification, and thus cause resistance to glycopeptide antibiotics, or mediate resistance against β-lactem antibiotics. In other cases the in vivo function is still unknown. New enzymes screened from nature, such as _D-aminopeptidase, _D-amino acid amidase, alkaline _D-peptidase or _D-aminoacylase, offer potential application in the production of _D-amino acids, the synthesis of _D-amino acid oligoners by promoting the reversed reaction under appropriate conditions, or in the field of semi-synthetic antibiotics.
- 公益社団法人日本生物工学会の論文
- 2000-04-25
著者
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Asano Yasuhisa
Biotechnology Research Center Toyama Prefectural University
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Asano Yasuhisa
Biotechnology Res. Center And Dep. Of Biotechnology Toyama Prefectural Univ.
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LUBBEHUSEN TINA
Biotechnology Research Center, Toyama Prefectural University
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Lubbehusen Tina
Biotechnology Research Center Toyama Prefectural University
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