Application of Bubble Column Fermntors to Submerged Culture of Schizophyllum commune for Production of L-Malic Acid
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概要
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To investigate the applicability of bubble column fermentors to the submerged culture of mushroom mycelia, cultivation of Schizophyllum commune IFO-4928 for production of L-malic acid was carried out using a standard bubble column and an external-loop airlift column. Maximum yields of L-malic acid were attained at a superficial air velocity of 0.7 cm/s for the standard bubble column and 1.7 cm/s for the external-loop airlift column. The optimum temperature was 27℃ for both types of column, and the optimum concentration of both calcium carbonate and glucose were 50 g/l. The yield of L-malic acid under opimum conditions for the airlift column was larger than for the standard bubble column. From the comparison of the production rates of L-malic acid in flask culture, a jar fermentor, an airlift column, and a standard buble column, the airlift bubble column was found to be most suitable for the culture of S. commune for L-malic acid production.
- 公益社団法人日本生物工学会の論文
- 1997-10-25
著者
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Miki Koujiro
Department Of Agricultural Chemistry Kyoto University
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Naoe Kazumitsu
Department of Chemical Engineering, Nara National College of Technology
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Kawagoe Mikio
Department Of Chemical Engineering Nara National College Of Technology
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Suye Shin-ichiro
Department Of Applied Chemistry And Biotechnology Graduate School Of Engineering University Of Fukui
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Suye Shin-ichiro
Department Of Biochemical Engineering Faculty Of Engineering Fukui University
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Naoe Kazumitsu
Department Of Chemical Engineering Nara National College Of Technology
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KAWAGOE MIKIKO
Department of Chemical Engineering, Nara National College of Technology
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HYAKUMURA KEIICHI
Department of Chemical Engineering, Nara National College of Technology
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Kawagoe Mikiko
Department Of Chemical Engineering Nara National College Of Technology
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Hyakumura Keiichi
Department Of Chemical Engineering Nara National College Of Technology
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