Polysaccharide from Aspalathus linearis with Strong Anti-HIV Activity
スポンサーリンク
概要
- 論文の詳細を見る
Polysaccharide that had been extracted with 1% sodium carbonate from Rooibos leaves (Aspalathus linearis) showed strong anti-HIV activity. Du-Zhong leaves also showed anti-HIV activity, although lower than the extract of Aspalathus linearis, but Japanese tea leaves and a hot water extract of Aspalathus linearis did not. The anti-HIV activity of the alkaline extract from Aspalathus linearis was recovered mainly in the 25-75% ethanol-precipitated fraction. The polysaccharide almost completely inhibited the binding of HIV-1 to MT-4 cells, It is inferred from these results that the polysaccharide from Aspalathus linearis is involved in the mechanism for virus binding to T cells.
- 社団法人日本農芸化学会の論文
- 1997-02-23
著者
-
Nakashima Hideki
Department of Microbiology and Immunologu,Kagoshima University Dental School
-
Nakashima Hideki
Department Of Advanced Energy Engineering Science Interdisciplinary Graduate School Of Engineering S
-
Nakashima Hideki
Graduate School Of Pharmaceutical Sciences Kyoto University
-
NAKANO Masatoshi
Institute for Medical Science of Aging
-
ITOH Yoshiko
Institute for Medical Science of Aging, Aichi Medical University
-
MIZUNO Toshiaki
Institute for Medical Science of Aging, Aichi Medical University
-
Itoh Yoshiko
Institute For Medical Science Of Aging Aichi Medical University
-
Mizuno Toshiaki
Institute For Medical Science Of Aging Aichi Medical University
-
Nakano M
Kyoto Univ. Kyoto Jpn
関連論文
- Relationship between Cytotoxic Activity and Radical Intensityof Isoflavones from Sophora Species
- Antimicrobial activity of trifluoromethyl ketones and theirsynergism with promethazine
- 再録報文 Anti-stress,Anti-HIV and Vitamin C-synergized Radical Scavenging Activity of Mulberry Juice Fractions
- Some Selective Serotonin Reuptake Inhibitors Inhibit Dynamin I Guanosine Triphosphatase (GTPase)(Biochemistry)
- Development of the Chemokine Receptor CXCR4 Antagonists as Multi-Pharmaceutical Agents Involving a New Class of Low Molecular Weight Antagonists
- P-423 Structure-Activity Relationship Studies on Cyclic Peptide-Based CXCR4 Antagonists
- Synthesis and Biological Evaluation of Peptidomimetic Analogs of the CXCR4 Antagonist FC131
- The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases Including AIDS, Cancer and Rheumatoid Arthritis
- New Leads of Low Molecular Weight CXCR4 Antagonists Based on Enhancement of the T140-based Pharmacophores
- A New Strategy for Molecular-size Reduction of Bioactive Peptide, Using Two Orthogonal Libraries of Cyclic peptides
- CXCR4 Antagonists Identified as Anti-Cancer-Metastatic Agents
- Synthesis of Novel Anti-HIV Peptides Based on a CXCR4 Antagonist, T140, and Their SAR Study
- Development of Specific CXCR4 Inhibitors Based on an Anti-HIV Peptide, T140, and Their Structure-Activity Relationships Study
- Increase of R5 HIV-1 infection and CCR5 expression in T cells treated with high concentrations of CXCR4 antagonists and SDF-1
- Sulfated Fibroin, a Novel Sulfated Peptide Derived from Silk, Inhibits Human Immunodeficiency Virus Replication in Vitro
- HIV-cell Fusion Inhibitors Targeted to the HIV Second Receptor : T22 and Its Downsized Analogs with High Activity
- Design, Synthesis and Activity of Shortened Analogs of an Anti-HIV Peptide, T22
- Helix Inducible Motifs Affect Helicity and Bioactivity of Anti-HIV Peptides
- Molecular Size of an Anti-HIV Peptide, T22, Can Be Reduced without Loss of the Activity
- STRUCTURE-ACTIVITY RELATIONSHIPS OF TACHYPLESIN ANALOGS AS ANTI-HIV AGENT
- STRUCTURES AND ACTIVITIES OF TANNINS IN CRUDE DRUGS (4) : EFFECTS ON PHAGOCYTES AND VIRUSES
- Effect of E2F decoy on inhibitation of neointima formation in pig coronary arteries after balloon injury and stent implantation
- Two-Dimensional Analysis of Energy Conversion Efficiency for a Traveling Wave Direct Energy Convertor
- Plasma Energy Recovery from a D-3^He Inertial Confinement Fusion Reactor
- Suprathermal Fusion Reactions in Laser-imploded DT Pellet and Its Applicability to Pellet Diagnosis
- Neutron Heating Effect in Laser-Imploded DT Pellet
- Relationship between Radical Intensity and BiologicalActivity of Cacao Husk Extracts
- Laser-Produced Plasma Experiments and Particle in Cell Simulation to Study Thrust Conversion Processes in a Laser Fusion Rocket
- Analysis of Exploding Plasma Behavior in a Dipole Magnetic Field
- Artificial Gene Regulation System Responding to HIV Protease
- Proliferation of mitogen-stimulated human peripheral blood mononuclear cells is inhibited by extracellular arginine deiminase of Granulicatella elegans isolated from the human mouth
- Analysis of Electron and Microwave Behavior in Microwave Discharge Neutralizer
- A Complete Rat Serum Albumin cDNA Clone Directly Identified by Immunological Screening of cDNA Expression Library(Biological Chemistry)
- Isolatin of Phage Library Clones with the Binding Activity to Anti-CCR5 Monoclonal Antibody (45531.111)
- Peptide-motif Analysis of Phage Clones Selected by Anti-CCR5 Monoclonal Antibody (2D7)
- In Vitro Anti-Human Immunodeficiency Virus Activity of Polysaccharide from Rhizophora mucronata Poir.
- Mangrove Halophytes: A source of antiviral substances
- Polysaccharide from Aspalathus linearis with Strong Anti-HIV Activity
- Analysis of ^Ni(n, α)Reaction Cross Sections with the Hauser-Feshbach Statistical Theory and the Bayesian Parameter Estimation Method
- Suppression of HIV-1 Reverse Transcriptase Activity by Culture Supernatants of Mycoplasmas
- Instability Analysis of Rotating Plasma in Stationary Gas
- Thrust Efficiency Calculation for Magnetic Nozzle in Laser Fusion Rocket
- Analysis of Exploding Plasma Behavior in a Dipole Magnetic Field
- Laser-Produced Plasma Experiments and Particle in Cell Simulation to Study Thrust Conversion Processes in a Laser Fusion Rocket
- Effects of Simultaneous Immunization of Haemophilus influenzae Type b Conjugate Vaccine and Diphtheria-Tetanus-Acellular Pertussis Vaccine on Anti-Tetanus Potencies in Mice, Guinea Pigs, and Rats
- Calculational Method for Neutron Heatingin Dense Plasma Systems, (II) Application to Burning D-T Pellets.:Application to Burning D-T Pellets
- Energy multiplication and fissile production of D-D fusion-fission hybrid reactors.
- Nuclear characteristics of D-D fusion reactor blanket. II. Thermal blanket and blanket-shield designs.:Thermal Blanket and Blanket-Shield Designs
- Control of thermal instability of pure and catalyzed D-D fusion reactor plasmas.
- Nuclear characteristics of gas-suspended boron carbide cooling catalyzed D fusion reactor blanket.
- Effects of neutron source ratio on nuclear characteristics of D-D fusion reactor blankets and shields.
- Calculational Method for Neutron Heating in Dense Plasma Systems, (I). Model and Formulation.
- Tritium breeding capability of heliotron-H fusion reactor blankets.
- Neutronics calculations for gas-suspended boron carbide cooling D-D fusion reactor blankets.
- Nuclear performance of two-phase flow cooling D-T fusion reactor blankets.
- Nuclear analysis of blanket/shield design for D-D tokamak fusion reactor.
- Nuclear design of heliotron fusion reactor blankets.
- Shield Optimization Study for Choke Coil of Tandem Mirror Fusion Reactor "GAMMA R"