Roles of the Dimethylamino Group and Macrodiolide Ring of Pamamycin-607 in Its Aerial Mycelium-inducing Activity
スポンサーリンク
概要
- 論文の詳細を見る
Four pamamycin-607-degraded products-desdimethylaminopa-mamycin-607, a macrodiolide ring-opened compound, and two constitutent hydroxy acid-were prepared, and their aerial mycelium-inducing activity was measured. The hydroxy acid L part with a dimethylamino group was the principal component responsible for activity. The macrodiolide ring itself was dispensable, but only hydroxy acid L showed very weak activity.
- 社団法人日本農芸化学会の論文
- 1995-09-23
著者
-
NATSUME Masahiro
Department of Applied and Biological Science, Faculty of Agriculture, Tokyo University of Agricultur
-
TANAKA Fumihiro
Department of Thoracic Surgery, Faculty of Medicine, Kyoto University
-
Kondo Satoru
Department of Cellular Neurobiology, Graduate School of Medicine, University of Tokyo
-
Kondo S
Department Of Applied Biosciences Nagoya University
-
HONDA Akira
Department of Pharmacology, College of Medicine, University of Vermont
-
Abe Hiroshi
Institute Of Symbiotic Science And Technology Tokyo University Of Agriculture And Technology
-
KONDO Satoru
School of Bioresources, Hiroshima Prefectural University
-
Tanaka Fumihiro
Department Of Applied Biosciences Nagoya University
-
MARUMO Shingo
Graduate School of Bioagricultural Sciences, Nagoya University
-
Abe H
Institute Of Symbiotic Science And Technology Tokyo University Of Agriculture And Technology
-
HONDA Aki
Applied Biological Chemistry, University of Tokyo
-
MARUMO Shingo
Department of Applied Biosciences, Nagoya University
-
Oshima Yoshiyuki
Department of Applied Biological Sciences, Tokyo University of Agriculture and Technology
-
Ase Hiroshi
Department of Applied Biological Sciences, Tokyo University of Agriculture and Technology
-
Honda Akira
Applied Biological Chemistry University Of Tokyo
-
Kondo S
Hiroshima Prefectural Univ. Hiroshima Jpn
-
Honda Akira
Department Of Materials Processing Faculty Of Engineering Tohoku University
-
Marumo S
Graduate School Of Bioagricultural Sciences Nagoya University
-
Marumo Shingo
Department Of Agricultural Chemistry Nagoya University
-
Natsume M
Institute Of Symbiotic Science And Technology Tokyo University Of Agriculture And Technology
-
Natsume Masahiro
Department Of Agricultural Chemistry Nagoya University
-
Oshima Yoshiyuki
Department Of Applied Biological Sciences Tokyo University Of Agriculture And Technology
-
Honda Akira
Department Of Chest Medicine School Of Medicine Chiba University
-
Kondo Satoru
Department Of Cellular Neurobiology Graduate School Of Medicine And Faculty Of Medicine The Universi
-
KONDO Satoru
Department of Agricultural Chemistry
-
MARUMO Shingo
Department of Agricultural Chemistry
関連論文
- PJ-504 Aortic Pulse Wave Velocity can Predict Left Ventricular Diastolic Dysfunction in a Community-based Population(PJ085,Heart Failure (Pathophysiology) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- 5 A Role of Endoplasmic Reticulum Stress in the Pathophysiology of Atherosclerotic Plaques Associated with Acute Coronary Syndrome(Vulnerable Patient/Vulnerable Plaque in Acute Coronary Syndrome,Plenary Session 2 (PL-2) (H),The 73rd Annual Scientific Meet
- Inhibition of Cardiac Remodeling by Pravastatin Is Associated with Amelioration of Endoplasmic Reticulum Stress
- Plasma Adiponectin Is Associated with Plasma Brain Natriuretic Peptide and Cardiac Function in Healthy Subjects
- PJ-763 Improvement of Left Ventricular Ejection Fraction is a Predictor for Cardiac Events in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical(diagnosis / treatment)(12)(IHD),Poster Session(Japanese),The 72nd Annual Scientif
- PJ-308 Miglitol, a Novel Alpha-Glucosidase Inhibitor, Improves Left Ventricular Function in Dogs With Pacing-Induced Heart Failure(Heart failure, basic(06)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-110 Transmural Heterogeneity of Global Gene Expression Profiles in Canine Failing Ventricular Myocardium(Heart failure, basic(05)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-091 Activation of AMP-activated Protein Kinase by Metformin Prevents Progression of Heart Failure in Dogs(Heart failure, basic(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-504 Aortic Pulse Wave Velocity can Predict Left Ventricular Diastolic Dysfunction in a Community-based Population(PJ085,Heart Failure (Pathophysiology) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- PE-482 Does Assessment of Atrial Contractile Properties Predict Paroxysmal Atrial Fibrillation? : A Color Doppler Strain Rate Imaging Study(PE081,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 4 (A),Poster Session (English),The 73rd Annual Scientific M
- OE-128 Left Ventricular Global Strain and Dyssynchrony Demonstrated by Speckle Tracking Echocardiography : A Comparison of Apical and Septal Right Ventricular Pacing(OE22,Echo/Doppler (Myocardium) (I),Oral Presentation (English),The 73rd Annual Scientific
- 5 A Role of Endoplasmic Reticulum Stress in the Pathophysiology of Atherosclerotic Plaques Associated with Acute Coronary Syndrome(Vulnerable Patient/Vulnerable Plaque in Acute Coronary Syndrome,Plenary Session 2 (PL-2) (H),The 73rd Annual Scientific Meet
- PJ-763 Improvement of Left Ventricular Ejection Fraction is a Predictor for Cardiac Events in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical(diagnosis / treatment)(12)(IHD),Poster Session(Japanese),The 72nd Annual Scientif
- PJ-218 Bachmann's Bundle Pacing Gets an Advantage over Right Atrial Appendage Pacing on Atrial Contraction Synchrony : A Strain Rate Imaging Study(Arrhythmia, therapy(24)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circu
- OJ-247 Influence of Preload Changes Mediated by Upper Body Tilting Position on Left Ventricular Diastolic Indices in chronic heart failure subjects(Echo / Doppler(04)(I),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circu
- 3 Management of Hyperphosphatemia is an Important Novel Therapeutic Target in Chronic Heart Failure(Symposium 11 (SY-11) (M) Stroke and Cardiorenal Complications in Hypertension,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulatio
- 3 Potential Pharmacological Adjunctive Therapy for Acute Myocardial Infarction : Lessons from J-WIND trials(Plenary Session 2 (PL-2) (IHD) Myocardial Protection Strategy after Reperfusion Therapy in Acute Coronary Syndrome,Special Program,The 72nd Annual
- Atorvastatin Slows the Progression of Cardiac Remodeling in Mice with Pressure Overload and Inhibits Epidermal Growth Factor Receptor Activation
- Long-Term Oral Administration of Dipyridamole Improves Both Cardiac and Physical Status in Patients with Mild to Moderate Chronic Heart Failure : A Prospective Open-Randomized Study
- Impact of Adenosine Receptor Signaling and Metabolism on Pathophysiology in Patients with Chronic Heart Failure
- PE-342 Novel Point-of-Care Test for Oxidative Stress, ROM Test, Reflects Elevated Oxidation Levels in the Patients with Chronic Heart Failure(Heart failure, clinical-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-250 A Novel Role of Histamine H2 Receptors in the Pathophysiology of Canine Heart Failure Induced by Sustained Rapid Pacing(Heart failure, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-092 Chronic Stimulation of Adenosine A2b Receptors Begun after Myocardial Infarction Prevents Cardiac Remodeling in Rats(Heart Failure, Cardiac Remodeling and Cardiomyopathy 2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-334 Measurement of the Plasma Adiponectin Level is Useful for the Prediction of Metabolic Syndrome : Result from KING Study(PJ056,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japan
- PJ-197 Common Variants in and around the Adiponectin Gene Associated with Plasma Adiponectin Level : Result from KING Study(PJ033,Preventive Medicine/Epidemiology/Education 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese
- PJ-192 Genetic Determinants of Plasma Resistin Levels in a Japanese Aged Cohort (KING Study)(PJ033,Preventive Medicine/Epidemiology/Education 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-048 Development of New Parenteral Inotrope : β_2 Adrenergic Agonist in Sticky Tape-form(Heart failure, basic-7 (M) PJ8,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Comparison of the Effects of Telmisartan and Olmesartan on Home Blood Pressure, Glucose, and Lipid Profiles in Patients with Hypertension, Chronic Heart Failure, and Metabolic Syndrome
- 4 Current Status and Surrounding Issues of Clinical Trials in Japan : Lesson and Proposal from our Experience of the Clinical Trials(Clinical Trials Update in Japan and Future Perspective, The 71st Annual Scientific Meeting of the Japanese Circulation Soc
- Abnormal Glucose Tolerance Contributes to the Progression of Chronic Heart Failure in Patients with Dilated Cardiomyopathy
- Intracellular Fate of 2-NBDG, a Fluorescent Probe for Glucose Uptake Activity, in Escherichia coli Cells
- PJ-506 Comparing Effects of Loop Diuretics with Antialdosteronergic Properties Versus Pure Loop Diuretics in Mildly Symptomatic Patients with Chronic Heart Failure(Heart failure, clinical(17)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting
- PE-166 Superoxide-Dependent Activation of Cathepsin System is Associated with Hypertensive Myocardial Remodeling and Represents a Target for AT1R Blocker Therapy(Cardiovascular pharmacology, basic/clinical(03)(H),Poster Session(English),The 72nd Annual Sc
- OE-366 Increased ^Tc-Sestamibi Washout Reflects Impaired Myocardial Contractile Reserve and Prolonged Relaxation in Patients with Nonobstructive Hypertrophic Cardiomyopathy(Nuclear cardiology(01)(I),Oral Presentation(English),The 72nd Annual Scientif
- PJ-494 Contraction Response to Dobutamine Could Predict Altered Myocardial Contractile Regulatory Proteins Expressions in Mildly Symptomatic Patients with Dilated Cardiomyopathy(Heart failure, clinical-14, The 71st Annual Scientific Meeting of the Japanes
- 1 Evidence for Human Atrial Natriuretic Peptide and Nicorandil as an Adjunct to Reperfusion Therapy for Acute Myocardial Infarction : J-WIND Trials(Late Breaking Clinical Trials in Japan, The 71st Annual Scientific Meeting of the Japanese Circulation Soci
- 3 Human Atrial Natriuretic Peptide and Nicorandil as an Adjunct to Reperfusion Therapy for Acute Myocardial Infarction : Lessons from J-WIND Trials(Discovery of Adjunctive Therapies for Acute Myocardial Infarction-From Bench to Bedside-, The 71st Annual S
- 4 Abnormal Glucose Tolerance as the Risk of Progression of Heart Failure or the Onset of Coronary Heart Disease(Diabetic Cardiovascular Complications and Therapeutic Strategy, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 6 Experience of Large-Scale Trial Using ANP or Nicorandil as an Adjunct to Percutaneous Coronary Intervention for Acute Myocardial Infarction(New Horizon in Coronary Interventions for Acute Coronary Syndrome, The 71st Annual Scientific Meeting of the Japa
- Angiogenesis and the efficacy of postoperative administration of UFT in pathologic stage I non-small cell lung cancer
- Expression of Thymidylate Synthase in Human Non-small Cell Lung Cancer
- p53 Status Predicts the Efficacy of Postoperative Oral Administration of Tegafur for Completely Resected Non-small Cell Lung Cancer
- Turnover of Synapse and Dynamic Nature of Synaptic Molecules In Vitro and In Vivo
- PJ-092 Activation of Adenosine A1 Receptors Inhibits Aldosterone Synthesis in Adrenal Glands(Metabolism/Biochemistry/Energetics-3 (M) PJ16,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PE-342 Dobutamine-Induced Mechanical Alternans Could be a Useful Predictor of Poor Prognosis in Ambulatory Patients with Idiopathic Dilated Cardiomyopathy(Heart failure, clinical(10)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Jap
- Membrane Stretch-Induced Activation of a TRPM4-Like Nonselective Cation Channel in Cerebral Artery Myocytes
- PJ-263 Tc-99m-sestamibi Washout Rate Could be Reflected Delayed Myocardial Relaxation in Patients with Hypertrophic Cardiamyopathy(Nuclear cardiology-7 (I) PJ45,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circu
- Stromal aminopeptidase N expression : correlation with angiogenesis in non-small-cell lung cancer
- OE-299 Myocardium Strain during Dobutamine Stress Echocardiography Discriminate Ischemic Heart Disease from Dilated Cardiomyopathy(Echo/Doppler-03, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Hyaline vascular-type Castleman's disease in the hepatoduodenal ligament : Report of a case
- Structure-activity Relationship of Pamamycins : Effect of Side Chain Length on Aerial Mycelium-inducing Activity
- Isolation and structural properties of aerial mycelium differentiation-inhibitory substances against Streptomyces scabiei causing potato common scab
- P-72 BIOSYNTHETIC PATHWAY OF PAMAMYCIN, A NITROGEN-CONTAINING POLYKETIDE
- Anthranilic Acid, a Spore Germination Inhibitor of Phytopathogenic Streptomyces sp. B-9-1 Causing Root Tumor of Melon
- Nitrogen Incorporation in the Biosynthetic Pathway of the Nitrogen-containing Polyketide, Pamamycin in Streptomyces alboniger
- Biosynthetic Origin of the Carbon Skeleton and Nitrogen Atom of Pamamycin-607, a Nitrogen-Containing Polyketide
- Relationship between Response to and Production of the Aerial Mycelium-inducing Substances Pamamycin-607 and A-factor(Microbiology & Fermentation Technology)
- De-N-methylpamamycin-593A and B, New Pamamycin Derivatives Isolated from Streptomyces alboniger
- UFT and S-1 for treatment of primary lung cancer
- The associated markers and their limitations for the primary screening of HCV carriers in public health examination
- Regulatory T cells and liver pathology in a murine graft versus host response model
- Deuterium-labeled Phaseic Acid and Dihydrophaseic Acids for Internal Standards(Organic Chemistry)
- Association of vitamin D and estrogen receptor gene polymorphism with the effects of longterm hormone replacement therapy on bone mineral density
- Effect of vitamin D receptor and estrogen receptor gene polymorphism on the relationship between dietary calcium and bone mineral density in Japanese women
- Synthesis, Absolute Configuration and Biological Activities of Both Enantiomers of 2-(5, 7-Dichloro-3-indolyl)propionic Acid : a Novel Dichloroindole Auxin and Antiauxin
- Synthesis, Absolute Configuration and Biological Activity of Both Enantiomers of 2-(5,6-Dichloro-3-indolyl) propionic Acid : New Dichloroindole Auxins
- Isolation and Characterization of an N-Linked Oligosaccharide That Is Significantly Increased in Sera from Patients with Non-Small Cell Lung Cancer
- Isolation of 2R, 5R-Dihydroxymethyl-3R, 4R-dihydroxypyrrolidine (DMDP) from the Fermentation Broth of Streptomyces sp. KSC-5791
- Vaccination with an immunodominant peptide of bovine type II collagen induces an anti-TCR response, and modulates the onset and severity of collagen-induced arthritis
- Teasterone-3-O-β-D-glucopyranoside, A New Conjugated Brassinosteroid Metabolite from Lily Cell Suspension Cultures and Its Identification in Lily Anthers
- Purification and Identification of New Acyl-conjugated Teasterones in Lily Pollen
- Structure-activity Relationship of Pamamycins:Effects of Alkyl Substituents
- Roles of the Dimethylamino Group and Macrodiolide Ring of Pamamycin-607 in Its Aerial Mycelium-inducing Activity
- Transient Increase in Intracellular Calcium in Streptomyces alboniger Produced by Pamamycin-607, an Aerial Mycelium-inducing Substance
- 3-Oxoteasterone and the Epimerization of Teasterone : Identification in Lily Anthers and Distylium racemosum Leaves and Its Biotransformation into Typhasterol
- Teasterone 3-Myristate: A New Type of Brassinosteroid Derivative in Lilium longiflorum Anthers
- Isolation, Structure and Biological Activity of Trialaphos(Organic Chemistry)
- Classification Method for Predicting the Development of Myocardial Infarction by Using the Interaction between Genetic and Environmental Factors
- Phytotoxin produced by Streptomyces sp. causing potato russet scab in Japan
- Phytotoxin Production and Aerial Mycelium Formation by Streptomyces scabies and S. acidiscabies in Vitro
- Amelioration of Subsoil Acidity in a Nonallophanic Andosol by Surface Application of Organic Calcium Salts
- 処理液のpHおよび生育ステ-ジの違いがレタスおよび葉ネギ葉部の外生アスコルビン酸含量に及ぼす影響
- Brassinolide and Homobrassinolide Promotion of Lamina Inclination of Rice Seedlings
- Accumulation of 7α-hydroxycholesterol in liver tissue of patients with cholesterol gallstones
- Increased bile acid concentration in liver tissue with cholesterol gallstone disease
- Synthesis of Brassinolide Analogs with a Modified Ring B and Their Plant Growth-promoting Activity(Organic Chemistry)
- A murine model of pulmonary basidiomycosis by Schizophyllum commune
- Arabidopsis CYP85A2 Catalyzes Lactonization Reactions in the Biosynthesis of 2-Deoxy-7-oxalactone Brassinosteroids
- Isolation and Characterization of a Spore Germination Inhibitor from Streptomyces sp. CB-1-1, a Phytopathogen Causing Root Tumor of Melon
- Cre complementation with variable dimerizers for inducible expression in neurons
- Chlamydospore-like Cell-inducing Substances of Fungi: Close Correlation between Chemical Reactivity with Methylamine and Biological Activity(Microbiology & Fermentation Industry)
- Treatment of Necrotic Infection on the Anterior Chest Wall Secondary to Mastectomy and Postoperative Radiotherapy by the Application of Omentum and Mesh Skin Grafting : Report of a Case
- Lung Cancer-related Genes in the Blood
- Malignant mesothelioma : current status and perspective in Japan and the world
- Oviposition Deterrents for the Limabean Pod Borer, Etiella zinckenella(TREITSCHKE)(Lepidoptera:Pyralidae)from Populus nigra L.c.v.Italica Leaves
- PA54 SPOROGEN-AO 1, AN ASEXUAL SPOROGENIC SUBSTANCE OF ASPERGILLUS ORYZAE
- UFT (Tegafur and Uracil) as Postoperative Adjuvant Chemotherapy for Solid Tumors (Carcinoma of the Lung, Stomach, Colon/Rectum, and Breast) : Clinical Evidence, Mechanism of Action, and Future Direction
- Identification and activity of ethyl gallate as an antimicrobial compound produced by Geranium carolinianum
- Alveolar Adenoma of the Lung : A Case Report
- Serum Blood Urea Nitrogen and Plasma Brain Natriuretic Peptide and Low Diastolic Blood Pressure Predict Cardiovascular Morbidity and Mortality Following Discharge in Acute Decompensated Heart Failure Patients