Multi-Detector Computed Tomography for Imaging of Subendocardial Infarction : Prediction of Wall Motion Recovery After Reperfused Anterior Myocardial Infarction

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概要

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• Background After reperfusion therapy for acute myocardial infarction (AMI), evaluation of transmural myocardial microcirculation can indicate prognosis. The aim of the present study was to determine whether the evaluation of transmural myocardial microcirculation by newly developed 4-slice computed tomography (CT) can estimate the recovery of left ventricular function. Methods and Results Seventeen consecutive patients who had anterior AMI with a total occlusion in the proximal left anterior descending artery (LAD) and who had undergone successful balloon reperfusion therapy within 24h of the onset of AMI were examined. Four-slice CT was performed 10-14 days after AMI onset. The median of the epicardial perfusion ratio (infarcted anterior epicardial CT number/intact lateral epicardial CT number ratio=92%) was used to categorize the cases into 2 groups: the transmural infarction group (n=8) and the subendocardial infarction group (n=9). Although no significant difference was observed between myocardial enhancement by CT in the acute phase and anterior wall motion or ejection fraction in the acute phase, the transmural infarction group showed poor recovery of anterior wall motion at 6 months after AMI onset, whereas the subendocardial infarction group exhibited good recovery of regional and global left ventricular function. Conclusions Transmural myocardial microcirculation imaged by 4-slice CT can predict wall motion recovery after AMI.

• 社団法人日本循環器学会の論文
• 2004-04-20

著者

• Ino Takashi

  First Department Of Integrated Medicine Omiya Medical Center Jichi Medical School

• Yasu Takanori

  First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University

• Kubo Norifumi

  First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University

• Kawakami Masanobu

  First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University

• Wada Hiroshi

  Saitama Medical Center Jichi Medical University

• Yasu Takanori

  First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University

• Kubo Norifumi

  First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University

• Tsuruya Yoshio

  Division Of Cardiology Saitama Social Insurance Hospital

• Saito Muneyasu

  First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University

• Yasu Takanori

  Department Of Clinical Pharmacology & Therapeutics University Of The Ryukyus Graduate School Of

• Kobayashi Yasuyuki

  First Department Of Integrated Medicine Omiya Medical Center Jichi Medical School

• Ishida Takeshi

  First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Saito Muneyasu

  First Department Of Integrated Medicine Omiya Medical Center Jichi Medical University

• Kawakami M

  First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University

• Wada Hiroshi

  First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Tsukamoto Yoshiaki

  First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Kobayashi Nobuhiko

  First Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School

• Kawakami Masanobu

  First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University

• Kobayashi Nobuhiko

  Department Of Medicine Jichi Medical School Omiya Medical Center

• Kanda Masaru

  Department Of Medicine Jichi Medical University Saitama Medical Center

• Kubo Norifumi

  Cardiovascular Division Jichi Medical University Saitama Medical Center

• Saito Muneyasu

  Cardiovascular Division Department Of Integrated Medicine I

• Tada Yuuko

  Division Of Cardiology Saitama Medical Center Jichi Medical School

• Turuya Yoshio

  Department Of Internal Medicine Saitama Medical Center Jichi Medical University

• Yasu Takanori

  First Department Of Integrated Medicine Omiya Medical Center Jichi Medical University

• Kanda M

  Department Of Surgical Neurology Jichi Medical School Omiya Medical Center

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