Close Association of Regional Interleukin-6 Levels in the Infarct-Related Culprit Coronary Artery With Restenosis in Acute Myocardial Infarction
スポンサーリンク
概要
- 論文の詳細を見る
Background The involvement of interleukin (IL)-6 in restenosis of the recanalized coronary artery after the percutaneous coronary intervention (PCI) was examined. Methods and Results There were 40 patients enrolled in the study who had acute myocardial infarction and whose infarct-related coronary arteries were treated by new thrombectomy devices and stenting. Blood samples were collected from the culprit coronary artery before and immediately after the maneuver of the PCI. Restenosis was defined as residural stenosis because it accounted for more than 50% at the follow-up coronary angiography. Plasma IL-6 levels in the infarct-related coronary artery were 12.8 and 13.2pg/ml before and after the initial maneuver of the PCI, respectively, values that were significantly greater than that of 7.2pg/ml in the peripheral vein (p<0.0001). The levels of IL-6 in the pre- and the post-stage of PCI were significantly greater in the patients with restenosis than those without restenosis. The plasma IL-6 levels in the post-stage of PCI had significant correlations with late loss and loss index. Conclusions The present study findings indicate that plasma IL-6 levels in the culprit coronary artery at the post-stage of PCI are closely associated with the future restenosis of the revasculized coronary artery in acute myocardial infarction.
- 社団法人日本循環器学会の論文
- 2006-03-20
著者
-
ISHIKAWA San-e
Department of Medicine, Jichi Medical University Saitama Medical Center
-
Ishikawa San-e
Department Of Integrated Medicine 1 Cardiovascular Division Jichi Medical University Saitama Medical
-
Ishikawa San-e
自治医科大学附属さいたま医療センター 循環器科
-
Ishikawa S
Department Of General Internal Medicine Omiya Medical Center Jichi Medical School
-
Ishikawa San-e
自治医科大学附属さいたま医療センター 内分泌代謝科
-
Ishikawa San-e
自治医科大学 腎臓内科学
-
Saito Muneyasu
Department Of Cardiology Tokyo Women's Medical University
-
Kubo Norifumi
First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University
-
Saito Muneyasu
First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University
-
Saito Muneyasu
The Cardiovasucural Division Jichi Medical School Omiya Medical Center
-
Yasu Takanori
Department Of Clinical Pharmacology & Therapeutics
-
Yasu Takanori
Department Of Clinical Pharmacology & Therapeutics University Of The Ryukyus Graduate School Of
-
KAWAKAMI Masanobu
Department of Medicine, Jichi Medical School
-
Funayama Hiroshi
Department of Internal Medicine, Saitama Medical Center, Jichi Medical University
-
Kubo Norifumi
Department of Internal Medicine, Saitama Medical Center, Jichi Medical University
-
Kawakami M
First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University
-
Kawakami Masanobu
Department Of Comprehensive Medicine Jichi Medical University Omiya Medical Center
-
Saito Muneyasu
Department Of Cardiology The Heart Institute Of Japan Tokyo Women's Medical University
-
Kanda Masaru
Department Of Medicine Jichi Medical University Saitama Medical Center
-
Kubo Norifumi
Division Of Cardiovascular Medicine Department Of Integrated Medicine I Jichi Medical University Sai
-
Ishikawa San-e
Department Of General Internal Medicine Omiya Medical Center Jichi Medical School
-
Kubo Norifumi
Cardiovascular Division Jichi Medical University Saitama Medical Center
-
Funayama Hiroshi
Cardiovascular Division Jichi Medical University Saitama Medical Center
-
Saito Muneyasu
Cardiovascular Division Department Of Integrated Medicine I
-
Tada Yuuko
Division Of Cardiology Saitama Medical Center Jichi Medical School
-
Yasu Takanori
Division Of Cardiovascular Medicine Department Of Integrated Medicine I Jichi Medical University Sai
-
Ishikawa San-e
Department Of Surgical Neurology Jichi Medical School Omiya Medical Center
-
Tada Yuko
Cardiovascular Division Department Of Medicine Jichi Medical University Saitama Medical Center
-
Kanda M
Department Of Surgical Neurology Jichi Medical School Omiya Medical Center
-
Yasu Takanori
Department Of Cardiovascular Respiratory And Metabolic Medicine Graduate School Of Medicine Kagoshima University
-
ISHIKAWA SAN-E
Department of Endocrinology and Metabolism, Jichi Medical School
-
Kubo Norifumi
Department of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University
-
Funayama Hiroshi
Department of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University
関連論文
- Serum adiponectin and markers of endothelial injury in hemodialysis patients with arteriosclerosis obliterans
- PJ-497 Cardiac Resynchronization Therapy Improves not Only Cardiac Function but Endothelial Function in Patients with Chronic Heart Failure(PJ084,CRT (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- In-hospital and One-year Outcome of Patients with Acute Myocardial Infarction after Reperfusion Therapy
- PE-017 Metabolic Syndrome Contributs to Aspirin-resistant Thromboxane Biosynthesis via Inducing Platelets COX-2 Expression in Patients with Stable Angina(Angina pectoris, basic/clinical-3 (IHD) PE3,Poster Session (English),The 70th Anniversary Annual Scie
- Effects of Submaximal Exercise on Blood Rheology and Sympathetic Nerve Activity
- The Functional Profiles of Circulating T Lymphocytes Distinguish Patients with Stable and Unstable Angina
- Use of Beta-blockers at Discharge in Patients With Acute Myocardial Infarction Data From the HIJC AMI data-base
- Renal Functions in Hypertensive Subjects Evaluated by Computer-aided Radioisotope Renogram : Prognosis and Treatment of Renal Hypertension
- Short and long term prognosis of non-ST-segment elevation MI(NSTEMI) : Multicenter study of HIJC group
- Prognostic risk stratification of in-hospital complications associated with acute myocardial infarction : HIJC group prospective cohort multicenter study
- Comparison of long-term clinical outcome of coronary stenting versus balloon angioplasty in acute myocardial infarction-Multicenter study of HIJC group
- Management and Evaluation of Non-supervised Home Exercise Program in a Convalescent Phase of Acute Myocardial Infarction : 53rd Annual Scienific Seeesion of the Japanese Circulation Society
- CHANGES IN EXERCISE TOLERANCE AFTER PERCUTANEOUS TRANSVENOUS MITRAL COMMISSUROTOMY(PTMC) : Exercise Test, Rehabilitation : 53 Annual Scientific Meeting, Japanese Circulation Society
- OJ-062 Matrix Metalloproteinase-9 Secretion from Vulnerable Plaque in Patients with Acute Coronary Syndrome : Optical Coherence Tomography Study(OJ11,ACS/AMI (Clinical/Diagnosis) (IHD),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The
- RELATIONSHIP OF HEART RATE, BLOOD PRESSURE, AND OXYGEN CONSUMPTION RESPONSES TO ORDINARY ACTIVITIES : Exercise Test (I) : FREE COMMUNICATIONS (V) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Advanced Glycation End Products Upregulate Endothelial COX-2 Expression and Induce Aspirin Resistant Thromboxane Synthesis by Platelets(Infection/Inflammation/Immunity 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-822 Predictors of Restenosis after Sirolimus Eluting Stent Implantation in the Real World(Coronary revascularization, PCI(26)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-444 Plaque Characterization in Chronic Kidney Patients Analyzed by Virtual Hestology Intravascular Ultrasound(Kidney/Renal circulation(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-234 Enhanced CD40 Ligand Levels are Associated with No Reflow Phenomenon and Left Ventricular Dysfunction in Patients with Acute Myocardial Infarction(Atherosclerosis, clinical(04)(IHD),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of
- Transient Mid-ventricular Ballooning Cardiomyopathy : A New Entity of "Takotsubo" Cardiomyopathy?(Cardiomyopathy, Clinical 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Vasospastic Total Occlusion at the Left Main Tract in a Single Coronary Artery
- -380- EFFICACY OF NON-SUPERVISED HOME EXERCISE PROGRAM IN CONVALESCENT PHASE OF ACUTE MYOCARDIAL INFARCTION : EVALUATION OF THE EFFECTS BY ANAEROBIC THRESHOLD
- -274- MECHANISMS OF IMPENDING MYOCARDIAL INFARCTION : RELATION WITH ST-SEGMENT SHIFTS DURING ISCHEMIC ATTACKS, INTRA-CORONARY THROMBUS AND FIXED STENOSIS OF THE CORONARY ARTERIES : Ischemic Heart Diseases : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 51t
- FRS-096 C-reactive protein upregulatesTLR-4 expression through NF-κB activation in vascular endothelial cells(Inflammation and Cardiovascular Disease (IHD) : FRS12)(Featured Research Session (English))
- 8 Clonally expanded T cells from coronary artery thrombus in patients with acute coronary syndrome(Plenary Session 2 (PL2) (IHD) : Inflammation and Atherosclerosis : From Bench to Bedside)(Special Program)
- HLA-DR and CD40 Ligand Expressing T Lymphocytes Are Increased in Circulation in Patients with Idiopathic Dilated Cardiomyopathy
- Application of the TIMI Risk Score for Predicting the Benefits of Triple Antiplatelet Therapy in Non-ST Elevation Acute Coronary Syndrome
- -554- EXERCISE INDUCED ST CHANGES AND RESIDUAL ISCHEMIA IN PREVIOUS MYOCARDIAL INFARCTION
- DIFFERENT CLINICAL PICTURES OF VASOSPASTIC ANGINA ACCORDING TO DISEASED VESSELS : Coronary Spasm : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Involvement of Arginine Vasopressin and Renal Sodium Handling in Pathogenesis of Hyponatremia in Elderly Patients
- Possible Pre-Cushing's Syndrome Due to an Adrenal Adenoma Incidentally Discovered
- Incomplete Deficiency of Hypothalamic Hormones in Hypothalamic Hypopituitarism Associated with an Old Traumatic Brain Injury
- Diabetes Mellitus as a Predictor of Retinopathy Associated With Acute Myocardial Infarction
- An Increase in Serum Retinol-Binding Protein 4 in the Type 2 Diabetic Subjects with Nephropathy
- PJ-454 Induction of Endothelial Cell Apoptosis and Monocyte Metalloproteinase-9 Production by C-Reactive Protein(PJ077,Infection/Inflammation/Immunity (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-132 Evaluation of Coronary Intervension by Optical Coherence Tomography in Patients with Acute Coronary Syndrome(PJ022,Coronary Revascularization, PCI (New Devices/New Technology) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of
- PJ-113 Effect of Statin Therapy on Plaque Volume and Composition in Patients with Acute Myocardial Infarction : A Virtual Histology Study(PJ019,Atherosclerosis (Clinical/Treatment) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of Th
- Determinants of in-hospital death in left main coronary artery myocardial infarction complicated by cardiogenic shock
- Pathogenesis of Chronic Hypernatremia with Dehydrated and Non-dehydrated States in Hypothalamic Space-occupying Lesions
- Daily Exercise and Bone Marrow-Derived CD34^+/133^+ Cells After Myocardial Infarction Treated by Bare Metal Stent Implantation
- PJ-471 Polyol Pathway Activation is More Contributed to Impaired Shear Stress-induced Endothelial Nitric Oxide Production in Hyperglycemia Than Oxidative Stress(Diabetes/Obesity/Metabolic syndrome(11)(H),Poster Session(Japanese),The 72nd Annual Scientific
- PJ-197 Increases in Metalloproteinase-8 in patients with acute myocardial infarction(Acute myocardial infarction, clinical (diagnosis/treatment)(09)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-004 Reduction of Neointimal Hyperplasia after Coronary Stenting by Pioglitazone in Nondiabetic Patients with Metabolic Syndrome(Coronary revascularization, PCI(05)(IHD),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circ
- New HLA DRB1 and DQB1 Haplotypes in a Pedigree of Familial Graves' Disease in Japan
- Determinants of In-Hospital Death and Rupture in Patients With a Stanford B Aortic Dissection
- Possibly Simultaneous Primary Aldosteronism and Preclinical Cushing's Syndrome in a Patient with Double Adenomas of Right Adrenal Gland
- PJ-555 Nateglinide Confers Protection against Apoptosis through Akt-and ERK1/2-Dependent Pathways in Cultured Cardiomyocytes(Cardiovascular pharmacology, basic/clinical-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- -P78- IMPROVEMENT OF REGIONAL THALLIUM UPTAKE AFTER CORONARY ANGIOPLASTY : AN IMPLICATION OF "STUNNED MYOCARDIUM" : RI : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- lmmunologically-Related or lncidental Coexistence of Dia-betes Mellitus and Graves' Disease; Discrimination by Anti-GAD Antibody Measurement
- Inhibition by Transforming Growth Factor-β1 of the Cellular Action of Arginine Vasopressin in Cultured Rat Glomerular Mesangial Cells
- Plasma Adrenomedullin Levels in Patients with Non-Insulin Dependent Diabetes Mellitus: Close Relationships with Diabetic Complications
- Inhibition by Adrenomedullin of Arginine Vasopressin-Activated Mitogen-Activated Protein Kinase in Rat Glomerular Mesangial Cells via cAMP Production
- PE-530 Clinical feasibility of Non-stress Contrast Echocardiography to Evaluate Coronary Stenosis in Acute Coronary Syndrome(Echo/Doppler(10)(I),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-690 Determinants of In-hospital Death and Rupture in Stanford B Aortic Dissections(Peripheral circulation/Vascular disease-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-260 Erythropoietin Protects Cultured Cardiomyocytes from Apoptosis Induced by Tumor Necrosis Factor-α(Cardiovascular pharmacology, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Evaluation of Transmural Myocardial Perfusion by Ultra-Harmonic Myocardial Contrast Echocardiography in Reperfused Acute Myocardial Infarction
- Rupture of the Anterolateral Papillary Muscle Caused by a Single Diagonal Branch Obstruction
- Plaque characterization of non-culprit lesions by virtual histology intravascular ultrasound in diabetic patients : Impact of renal function
- PJ-502 Plasma Placental Growth Factor Level in the Patients with Congestive Heart Failure(Heart failure, clinical-15, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-385 Prompt Changes in the Plaque Composition of a Non-culprit Coronary Artery in Patients with AMI : A Virtual histology study(Intravascular endoscopy/Intravascular ultrasound-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Association of Hyperadiponectinemia With Severity of Ventricular Dysfunction in Congestive Heart Failure
- Close Association of Regional Interleukin-6 Levels in the Infarct-Related Culprit Coronary Artery With Restenosis in Acute Myocardial Infarction
- PJ-200 Association of Hyperadiponectinemia with Severity of Ventricular Dysfunction in Congestive Heart Failure(Heart failure, clinical-11 (M) PJ34,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Societ
- PJ-088 Relation between Lipid Parameters and Coronary Plaque Composition : A Virtual Histology Analysis(Intravascular endoscopy/Intravascular ultrasound-6 (I) PJ15,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
- PE-508 Myeloperoxidase May Contribute to the No-reflow Phenomenon in Patients with Acute Myocardial Infarction(Myocardial ischemia-reperfusion, basic/clinical-3 (IHD) PE85,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japa
- OJ-253 Matrix Metalloproteinase-9 may be a New Biomarker for Coronary Plaque Rupture in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (pathophysiology)-2 (IHD) OJ43,Oral Presentation (Japanese),The 70th Anniversary Annual
- Local Accumulation of Adiponectin in Coronary Circulation in Patients with Ischemic Heart Disease (Atherosclerosis, Clinical 10 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Increases in Plasma Arginine Vasopressin and Urinary Excretion of Aquaporin-2 Water Channel in Congestive Heart Failure(Heart Failure, Clinical 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- -P178- SERIAL CHANGES IN NUCLEAR MAGNETIC RESONACE SIGNAL INTENSITY OF MYOCARDIAL INFARCT ZONE
- -259- CLINICAL EVALUATION OF COMPLETION PROCESS OF MYOCARDIAL NECROSIS IN ACUTE MYOCARDIAL INFARCTION : Ischemic Heart Diseases : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Hepatocyte growth factor inhibits production of matrix metalloprotease-9 induced by monocyte-vascular endothelial cell interaction
- Monocyte-vascular endothelial cell interaction inhibits apoptosis of vascular endothelial cells by inducing Bcl-2
- Unilateral Adrenalectomy Improves Insulin Resistance and Diabetes Mellitus in a Patient with ACTH-Independent Macronodular Adrenal Hyperplasia
- Chronic Hypernatremia Derived from Hypothalamic Dysfunction: Impaired Secretion of Arginine Vasopressin and Enhanced Renal Water Handling
- Clinical Implication of Serial Leptin Measurement in Subjects with Type 2 Diabetes Mellitus
- Crucial Role of Insulin in Leptin Maintenance: Profound Decrease in Serum Leptin by Octreotide Acetate in Insulinoma Subjects
- Inverse Distribution of Serum Sodium and Potassium in Uncontrolled Inpatients with Diabetes Mellitus
- Contribution of a Missense Mutation (Trp64Arg) in β3-Adrenergic Receptor Gene to Multiple Risk Factors in Japanese Men with Hyperuricemia
- Inhibitory Effect of BQ-123 on Endothelin-1-Stimulated Mitogen-Activated Protein Kinase and Cell Growth of Rat Vascular Smooth Muscle Cells
- Effect of Glycemic Control on Calcium and Phosphorus Handling and Parathyroid Hormone Level in Patients with Non-Insulin-Dependent Diabetes Mellitus
- Direct evidence of altered bone metabolixm caused by all-trans retinoic acid
- Circulating CD34^+/133^+ Progenitor Cells in Patients With Stable Angina Pectoris Undergoing Percutaneous Coronary Intervention
- Effects of a Distal Protection Device During Primary Stenting in Patients With Acute Anterior Myocardial Infarction
- Exercise after Heparin Administration, A New Therapeutic Program for Patient with Arteriosclerosis Obliterans
- Clinical and laboratory features of hyponatremia-induced myopathy
- Unilateral Active Adrenal Tuberculosis Featuring Persistent Intermittent Fever
- SIADH Closely Associated with Non-functioning Pituitary Adenoma
- Full-Blown Cushing's Disease after an Episode of Pituitary Apoplexy
- Contrast-Enhanced Endoscopic Ultrasonography Improves the Preoperative Localization of Insulinomas
- Influence of Contrast Ultrasonography With Perflutren Lipid Microspheres on Microvessel Injury
- Regional Interleukin-6 Levels in the Culprit Coronary Artery after Coronary Angioplasty May Predict Restenosis in Acute Myocardial Infarction
- Postcholecystectomy Syndrome Mimicking Angina Pectoris Detected by the Morphine Provocation Test
- Left Ventricular Dysfunction Activates Barorecepter-Mediated Arginine Vasopressin Release in Congestive Heart Failure
- Elevated levels of interleukin-6 in infarct-related Coronary Artery in patients with acute myocardial infarction
- PJ-050 Interleukin-8 may contribute to the no-reflow phenomenon in patients with acute myocardial infarction(Acute Myocardial Infarction, Clinical (Pathophysiology) 2 (IHD) : PJ9)(Poster Session (Japanese))
- Amphotericin B-induced Nephrogenic Diabetes Insipidus
- Increases in Interleukin-6 and Matrix Metalloproteinase-9 in the Infarct-Related Coronary Artery of Acute Myocardial Infarction
- Early Development of Hyponatremia Implicates Short- and Long-Term Outcomes in ST-Elevation Acute Myocardial Infarction
- EFFECTS OF 5-FLUOROURACIL ON CARDIAC FUNCTION AND METABOLISM IN ISOLATED PERFUSED RAT HEART : Myocardial Metabolism : IV Auditorium : PROCEEDINGS OF THE 44th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Association of subcutaneous and visceral fat mass with serum concentrations of adipokines in subjects with type 2 diabetes mellitus