Effects of a Distal Protection Device During Primary Stenting in Patients With Acute Anterior Myocardial Infarction
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概要
- 論文の詳細を見る
Background The angiographic no-reflow phenomenon is an adverse prognostic factor in patients with acute myocardial infarction (AMI). The aim of the present study was to evaluate the effects of an occlusive balloon type distal protection device (PercuSurge GuardWire: GW) during primary stenting in patients with anterior AMI. Methods and Results The GW group included 42 patients treated by primary stenting with GW protection and the control group included 30 patients treated by primary stenting after thrombectomy without distal protection. Left ventricular (LV) function was measured and compared by left ventriculography obtained soon after percutaneous coronary intervention (PCI) and 3 weeks after onset. The corrected TIMI frame count values were lower in the GW group than in the control group (27.5±2.3 vs 35.1±2.5, p=0.030). The number of patients with myocardial blush grade 3 after PCI was higher in the GW group than in the control group (45.7 vs 20.0%, p=0.029). Peak concentration of creatine kinase myocardial fraction was lower in the GW group than in the control group (326.6±41.5 vs 454.9±46.2mg/dl, p=0.043). GW patients showed greater improvement at 3 weeks after PCI in terms of LV ejection fraction (+4.6±1.2 vs -1.1±1.5, p=0.004), LV end-systolic volume index (+0.5±2.4 vs +9.0±2.7, p=0.023), and regional wall motion abnormalities (-2.03±0.14 vs -2.51±0.14, p=0.018). Conclusion Primary stenting with GW protection can restore epicardial coronary flow and myocardial perfusion, and also preserve LV function in anterior AMI.
- 社団法人日本循環器学会の論文
- 2004-07-20
著者
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Ino Takashi
First Department Of Integrated Medicine Omiya Medical Center Jichi Medical School
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ISHIDA Takeshi
Department of Clinical Laboratory, Osaka University Faculty of Dentistry
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Hashimoto Shigemasa
Department of Cardiovascular Medicine, Saga Medical School
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Saito Muneyasu
Department Of Cardiology Tokyo Women's Medical University
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Ikeda Nahoko
First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University
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Ikeda Nahoko
First Department Of Integrated Medicine Omiya Medical Center Jichi Medical University
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Saito Muneyasu
First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University
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FUJII Mikihisa
Department of Cardiology,Jichi Medical School
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Yasu Takanori
Department Of Clinical Pharmacology & Therapeutics
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Yasu Takanori
Department Of Clinical Pharmacology & Therapeutics University Of The Ryukyus Graduate School Of
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KAWAKAMI Masanobu
Department of Medicine, Jichi Medical School
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Hashimoto Shigemasa
Department Of Cardiovascular And Renal Medicine Saga University Faculty Of Medicine
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Funayama Hiroshi
Department of Internal Medicine, Saitama Medical Center, Jichi Medical University
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Nakamura Tomohiro
Department of Internal Medicine, Saitama Medical Center, Jichi Medical University
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Kubo Norifumi
Department of Internal Medicine, Saitama Medical Center, Jichi Medical University
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Ikeda Nahoko
Department of Cardiovascular Medicine, Jichi Omiya Medical Center
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Kawakami M
First Department Of Integrated Medicine Saitama Medical Center Jichi Medical University
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Kawakami Masanobu
Department Of Comprehensive Medicine Jichi Medical University Omiya Medical Center
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Saito Muneyasu
Department Of Cardiology The Heart Institute Of Japan Tokyo Women's Medical University
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Nakamura Tomohiro
Department Of General Education Osaka Institute Of Technology
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Kanda Masaru
Department Of Medicine Jichi Medical University Saitama Medical Center
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Fujii Mikihisa
Cardiovascular Division First Department Of Integrated Medicine Omiya Medical Center Jichi Medical S
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Fujii Mikihisa
Department Of Cardiology Jichi Medical School
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Fujii Mikihisa
Department Of Integrated Medicine 1 Jichi Medical School Omiya Medical Center
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Seki Yuichi
Department of Integrated Medicine, Omiya Medical Center, Jichi Medical School
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Seki Yuichi
Department Of Integrated Medicine Omiya Medical Center Jichi Medical School
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Kubo Norifumi
Cardiovascular Division Jichi Medical University Saitama Medical Center
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Funayama Hiroshi
Cardiovascular Division Jichi Medical University Saitama Medical Center
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Saito Muneyasu
Cardiovascular Division Department Of Integrated Medicine I
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Kanda M
Department Of Surgical Neurology Jichi Medical School Omiya Medical Center
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Yasu Takanori
Department Of Cardiovascular Respiratory And Metabolic Medicine Graduate School Of Medicine Kagoshima University
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Ikeda Nahoko
Division Of Cardiovascular Medicine Department Of Integrated Medicine I Jichi Medical University Saitama Medical Center
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NAKAMURA Tomohiro
Department of Cardiovascular Surgery, Uji Tokushukai Hospital
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Kubo Norifumi
Department of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University
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Funayama Hiroshi
Department of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University
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