EFFECTS OF CORONARY THROMBOLYSIS ON LEFT VENTRICULAR EJECTION FRACTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

スポンサーリンク

概要

• 論文の詳細を見る

• Left ventriculograms were performed on 65 patients with acute myocardial infarction, once upon admission and again 3 months later. In 29 cases urokinase was injected intravenously and/or intracoronarily. The other 17 were treated without urokinase. In 8 out of 29 patients whose infarct-related coronary arteries remained completely occluded following urokinase therapy, the global ejection fraction was reduced from 54 ± 3% during the acute stage to 46 ± 5% during the chronic stage (p < 0.001). However, for the 21 patients whose coronary arteries were successfully recanalized, the 2 values were the same (52 ± 2%). The highest global ejection fractions were seen in 19 spontaneously recanalized patients (acute: 54 ± 2%, chronic: 55 ± 2%). For the 8 unsuccessful patients, the regional ejection fraction for the infarcted portion was reduced from 20 ± 5% during the acute stage to 18 ± 6% during the chronic stage. But for the successful patients there was an improvement from 22 ± 2% during the acute stage to 27 2% during the chronic stage. Again, the regional ejection fraction was the highest for the spontaneously recanalized group, being 31 2% and 36 3% during the acute and chronic stages, respectively. These results indicate that if the coronary artery remains occluded during the acute stage the reduced left ventricular function continues to deteriorate even more during the chronic stage. Successful coronary thrombolysis, however, might salvage the infarcted myocardium as well as preserve the function of the left ventricle.

• 社団法人日本循環器学会の論文
• 1988-10-20

著者

• Ohno Makoto

  The First Department Of Internal Medicine Kinki University School Of Medicine

• Koka H

  First Department Of Internal Medicine Kinki University School Of Medicine

• KATORI Ryo

  First Dept. of Inter. Med Tohoku Univ. School of Med.

• ISHIKAWA Kinji

  First Dept. of Inter. Med Tohoku Univ. School of Med.

• OGAWA Iwao

  First Department of Internal Medicine,Kinki University School of Medicine

• KANAMASA Ken

  First Department of Internal Medicine,Kinki University School of Medicine

• SHIMIZU MINORU

  First Department of Internal Medicine, Kinki University School of Medicine

• MORISHITA MASATAKA

  First Department of Internal Medicine, Kinki University School of Medicine

• KOKA HIRONARI

  First Department of Internal Medicine, Kinki University School of Medicine

• Oda Akio

  First Department of Medicine, Kinki University School of Medicine

• Kanamasa Ken

  近畿大学 医学部高血圧・老年内科部門

• Morishita Masataka

  Division Of Cardiology Department Of Internal Medicine Kinki University School Of Medicine

• Ishikawa Kinji

  First Department Of Internal Medicine Kinki University School Of Medicine

• Koka Hironari

  First Department Of Internal Medicine Kinki University School Of Medicine

• Kato A

  First Department Of Internal Medicine Kinki University

• Katori Ryo

  First Department Of Internal Medicine Kinki University School Of Medicine

• Ono Makoto

  The First Department Of Internal Medicine Kinki University School Of Medicine

• Oono Makoto

  First Department Of Internal Medicine Kinki University School Of Medicine

• Shimizu Minoru

  The First Department Of Internal Medicine Kinki University School Of Medicine

• ONO MAKOTO

  First Department of Internal Medicine, Kinki University School of Medicine

• Okayama Akihiko

  First Department Of Internal Medicine Kinki University School Of Medicine

• Ogawa I

  Shiroyama Hospital

• Oono Makoto

  The First Department Of Internal Medicine Kinki University School Of Medicine

• Oda A

  Kinki Univ. Osaka Jpn

• Katori Ryo

  The First Department Of Internal Medicine Kinki University School Of Medicine Osaka

• OGAWA Iwao

  First Department of Internal Medicine, Kinki University School of Medicine

• KANAMASA Ken

  First Department of Internal Medicine, Kinki University School of Medicine

関連論文

• COUNTERLATERAL CORONARY CIRCULATION AND MYOCARDIAL METABOLISM IN CORONARY ARTERY BRANCH OCCLUSION AND CONSTRICTION DOGS : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
• A mechanism and clinical implications of exercise-induced ST-segment elevation in patients recovering from myocardial infarction
• EXERCISE-INDUCED ST-SEGMENT ELEVATION AND HEMODYNAMIC RESPONSES ONE MONTH AFTER MYOCARDIAL INFARCTION
• COMPARISON OF INTRAVENOUS t-PA AND CONSERVATIVE THERAPY FOR ACUTE MYOCARDIAL INFARCTION IN MULTICENTER TRIAL: RESULTS OF THE SOUTH OSAKA MYOCARDILAL INFARCTION(SOMI)PHASE I TRIAL
• EXERCISE-INDUCED ST-SEGMENT ELEVATION AND REGIONAL MYOCARDIAL BLOOD FLOW IN DOGS WITH TRANSMURAL MYOCARDIAL INFARCTON
• CLINICAL SIGNIFICANCE OF ABNORMAL Q WAVE DISAPPEARANCE IN ACUTE TRANSMURAL MYOCARDIAL INFARCTION
• -0732-LATE REPERFUSION AFTER MYOCARDIAL INFARCTION PRESERVES VENTRICULAR FUNCTION
• -0592-CRITICAL FLOW REQUIREMENT TO PREVENT STUNNED MYOCARDIUM AS MEASURED BY NON-RADIOACTIVE COLORED MICROSPHERE IN DOGS
• A POSSIBLE MECHANISM OF REGIONAL HYPERKINESIS AT THE NON-INFARCTED AREA IN ACUTE MYOCARDIAL INFARCTION : Pathophysiology : 53 Annual Scientific Meeting, Japanese Circulation Society
• EFFICACY OF CORONARY THROMBOLYSIS AND SECONDARY PREVENTION AFTER THROMBOLYSIS IN ACUTE MYOCARDIAL INFARCTION : Coronary Thrombolysis : 53 Annual Scientific Meeting, Japanese Circulation Society
• -7-CONCOMITANT CHANGES OF ST-SEGMENT AND T AMPLITUDE DURING EXERCISE-INDUCED ST ELEVATION IN ANTERIOR MYOCARDIAL INFARCTION : Excercise Test : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• CONTRIBUTION OF COUNTERLATERAL CORONARY ARTERY LESIONS ON THE GENESIS OF THE ST SEGMENT ELEVATION OR DEPRESSION IN MYOCARDIAL ISCHEMIA : Arrhythmias (II), Electrophysiology (II), Mapping : III : 48 Annual Scientific Meeting, Japanese Circulation Society
• Primary cardiac lymphoma as a complication of Sjogren's syndrome
• A coin lesion due to pulmonary infarction : a case report
• Ruptured plaque versus non-ruptured eroded plaque of culprit iesions in acute myocardial infarction patients : Angioscopy and IVUS study in vivo
• EFFECT OF 40% OR 100% OXYGEN (02) BREATHING ON THE ISCHEMIC MYOCARDIUN IN DOGS : Cardiac Performance : Ist Auditorium : Proceedings of the 43rd Annual Meeting of the Japanese Circulation Society, Tokyo, 1979
• Retrospective Analysis Showing Less Cardiac Events in Post-Myocardial Infarction Patients Treated With Metoprolol
• β-adrenergic stimulation can induce ST-segment elevation without evolution of left ventricular dilation or myocardial ischemia one month after myocardial infarction
• Increased regional myocardial blood flow in peri-infarct area during exercise-induced ST-segment elevation in canine myocardial infarction
• 0574 Effects of CX397, a Novel Hirudin Analog, as Adjuncts to Coronary Thrombolysis with rt-PA
• RESPONSE OF LEFT VENTRICULAR ENDSYSTOLIC PRESSURE-VOLUME RELATION AFTER CORONARY THROMBOLYSIS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION : Coronary Thrombolysis : 53 Annual Scientific Meeting, Japanese Circulation Society
• EFFECTS OF LONG USE OF A β-BLOCKER, CARTEOLOL, ON EXERCISE HEMODYNAMICS IN HYPERTENSIVES
• INCREASE OF REGIONAL LEFT VENTRICULAR MUSCLE STIFFNESS BY ATRIAL PACING IN PATIENTS WITH ISCHEMIC HEART DISEASE : Cardiac Function(II) : II : 48 Annual Scientific Meeting, Japanese Circulation Society
• ABNORMAL REGIONAL SHORTENING AND LENGTHENING IN MYOCARDIAL CONTRACTION OF LEFT VENTRICULAR ECTOPIC BEAT IN ANESTHETIZED DOGS : Cardiac Function(II) : II : 48 Annual Scientific Meeting, Japanese Circulation Society
• -0879-DECREASE IN LYSIS OF OLD THROMBI AFTER RAPID ADMINISTRATION OF TISSUE-TYPE PLASMINOGEN ACTIVATOR : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Diagnosis of Ischemic Heart Disease with Exercise Echocardiography : Comparison of Images Obtained at Peak- and Post-Exercise
• EFFECT OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST, TCV-116, ON RAT CAROTID ARTERY NEOINTIMA FORMATION AFTER BALLOON INJURY
• ANTISENSE ODNS FOR C-MYC MRNA PRODUCED SIGNIFICANT INHIBITION IN THE HYPERTROPHIC EFFECT OF ANGIOTENSIN II ON VASCULAR SMOOTH MUSCLE CELLS
• ATRIAL NATRIURETIC PEPTIDE AND ANTIHYPERTENSIVE ACTION DUE TO β-BLOCKADE IN ESSENTIAL HYPERSIVE PATIENTS
• IS PROTEIN KINASE C(PKC)ACTIVATION ESSENTIAL FOR THE HYPERTROPHIC EFFECT OF α_1-ADRENERGIC STIMULATION?
• -0503-ENDOTHELIN INDUCED HYPERTROPHY OF CULTURED HEART CELLS
• INHIBITORY EFFECT OF TAURINE ON CARDIAC MYOCYTE HYPERTROPHY IN CULTURED RAT NEONATAL VENTRICLES : Myocardial Metabolism, Biochemistry : 53 Annual Scientific Meeting, Japanese Circulation Society
• -P107-RENAL GLOGERULAR α-RECEPTORS IN M-STRAIN OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RAT (M-SHRSP) : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -343- EFFECT OF ATRIAL NATRIURETIC PEPTIDE ON ALDOSTERONE RECEPTOR IN RAT KIDNEY CYTOSOL
• Aspirin Plus Either Dipyridamole or Ticlopidine is Effective in Preventing Recurrent Myocardial Infarction
• -1289- EFFECTS OF ELECTIVE CORONARY ANGIOPLASTY ON CARDIAC EVENTS IN PATIENTS WITH HEALED MYOCARDIAL INFARCTION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• -1148- IMPROVED PROGNOSIS DURING LONG-TERM TREATMENT WITH β-BLOCKERS IN PATIENTS WITH HEALED MYOCARDIAL INFARCTION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• -0171- LONG TERM TREATMENT WITH LIPID-LOWERING AGENTS REDUCED CORONARY EVENTS IN PATIENTS WITH HEALED MYOCARDIAL INFARCTION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• -0019- EFFECT OF ANTIPLATELET AGENTS TO PREVENT CARDIAC EVENTS IN PATIENTS WITH HEALED MYOCARDIAL INFARCTION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• EFFECTS ON ANTI IC DRUGS FOR CARDIAC DEATH IN PATIENTS WITH HEALED MYOCARDIAL INFARCTION
• EFFECTS OF β-BLOCKERS ON CARDIAC EVENTS IN PATIENTS WITH HEALED MYOCARDIAL INFARCTION
• NITRATES INCREASED CARDIAC EVENTS IN PATIENTS WITH HEALED MYOCARDIAL INFARCTION
• Effect of Ca antagonists on the prevention of recurrent myocardial infarction
• LOW DOSE ASPIRIN COMBINED WITH EITHER DIPYRIDAMOLE OR TICLOPIDINE PREVENTS RECURRENT MYOCARDIAL INFARCTION IN ANGINA PECTORIS FOLLOWING MYOCARDIAL INFARCTION
• EFFECT OF PREINFARCTION ANGINA ON LEFT VENTRICULAR SYSTOLIC FUNCTION IN ACUTE MYOCARDIAL INFARCTION(MI)
• -1225-RELATIONSHIP BETWEEN LEFT VENTRICULAR DIASTOLIC FILLING BY PULSED DOPPLER ECHOCARDIOGRAPHY AND LEFT VENTRICULAR RELAXATION IN ISCHEMIC HEART DISEASE : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• P143 CORONARY ANGIOSCOPIC FINDINGS OBTAINED 24 TO 48 HOURS AFTER SUCCESSFUL THROMBOLYSIS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
• Haziness after percutaneous transluminal coronary angioplasty in quantitative coronary angiographic analysis
• Angioscopic evaluation of intracoronary thrombus after PTCA and its relation with restenosis
• PREDICTION OF HIBERNATING MYOCARDIUM IN PATIENTS WITH MYOCARDIAL INFARCTION BY ELECTIVE CORONARY ANGIOPLASTY
• -P521- EFFECTS OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST, TCV-116, ON NEOINTIMAL FORMATION FOLLOWING BALLOON INJURY IN SHR CAROTID ARTERY(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• Reduced mortality by coronary thrombolysis with urokinase in acute myocardial infarction
• EFFECTS OF CORONARY THROMBOLYSIS ON LEFT VENTRICULAR EJECTION FRACTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
• REDUCED EARLY DIASTOLIC EXTENSION IN THE INFARCTED PORTION IN PATIENTS WITH OLD MYOCARDIAL INFARCTION
• -268- ANGIOGRAPHIC APPEARANCE OF CORONARY OCCLUSIVE LESIONS AND EFFECTIVENESS OF THROMBOLYSIS BY UROKINASE IN ACUTE MYOCARDIAL INFARCTION : Ischemic Heart Diseases : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANE
• CALCULATION OF REGIONAL LEFT VENTRICULAR WORK USING REGIONAL TENSION-AREA LOOP BY THE PROLATE SPHEROID MODEL IN MAN : Cardiac Function (II) : FREE COMMUNICATIONS (IV) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Role of Cardiac ATP-Sensitive K^+ Channels Induced by HMG CoA Reductase Inhibitor in Ischemic Rabbit Hearts
• Role of Cardiac ATP-Sensitive K^+ Channels Induced by Angiotensin II Type 1 Receptor Antagonist on Metabolism, Contraction and Relaxation in Ischemia-Reperfused Rabbit Heart
• Effect of Angiotensin Converting Enzyme Inhibitor and Angiotensin II Type 1 Receptor Antagonist on Metabolism and Contraction in Ischemia-Reperfused Rabbit Heart
• Effect of an Endothelin Receptor Antagonist and an Angiotensin Converting Enzyme Inhibitor on Metabolism and Contraction in the Ischemic and Reperfused Rabbit Heart
• P671 EFFECTS OF THE ANGIOTENSIN-CONVERTING ENZYME INHIBITOR IN CARDIAC HYPERTROPHY IN TSUKUBA
• Relationship Between Blood Pressure and Cardiac Events in Patients With a Healed Myocardial Infarction
• Coronary collaterals present after acute anterior myocardial infarction prevent left ventricular aneurysm formation
• Increased Coronary Vasomotor Tone in Acute Myocardial Infarction Patients With Spontaneous Coronary Recanalization
• Role of the Renin-Angiotensin System in Cardiac Hypertrophy and Renal Glomerular Sclerosis in Transgenic Hypertensive Mice Carrying Both Human Renin and Angiotensinogen Genes
• Recombinant Tissue Plasminogen Activator Prevents Intimal Hyperplasia After Balloon Anigioplasty in Hypercholesterolemic Rabbits
• 0176 Intramyocardial Injection of Basic Fibroblast Growth Factor(bFGF)at the Infarcted Myocardium Increased Regional Myocardial Blood Flow and Viable Myocardium 4 Weeks Later in Dogs
• Regional blood flow in infarcted myocardium of basic fibroblast growth factor-treated rats
• Contralateral arterial bolus injection of 30 micrograms of basic fibroblast growth factor failed to augment myocardial blood flow in infarcted myocardium in dogs
• Seven day tPA or heparin administration prevents intimal hyperplasia after balloon angioplasty in atherosclerotic rabbits
• REGIONAL MYOCARDIAL BLOOD FLOW OF EPICARDIAL RIM AT THE HEALED INFARCT EXCEEDED NORMAL FLOW IN DOGS
• PREVENTION OF INTIMAL HYPERPLASIA FOLLOWING BALLOON ANGIOPLASTY BY CONTINUOUS 7 DAY tPA INFUSION IN ATHEROSCLEROTIC RABBITS
• COLLATERAL FLOW DEVELOPED WITHIN 3 HOURS AFTER CORONARY OCCULUSION MINIMIZED MYOCARDIAL NECROSIS IN DOGS
• Inhibitory Effects of a Subdepressor Dose of L-158, 809, an Angiotensin II Type 1 Receptor Antagonist, on Cardiac Hypertrophy and Nephropathy Via the Activated Human Renin-Angiotensin System in Double Transgenic Mice With Hypertension
• Myocardial Salvage by Reperfusion 12 Hours After Coronary Ligation in Dogs
• SD-3212 blocks the inward rectifier potassium channel in guinea pig ventricular myocytes
• MYOCARDIAL CONTRACTILE IMPAIRMENT IN RELATION TO MYOCARDIAL FIBER ORIENTATION DURING ISCHEMIA IN DOGS : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Coronary Circulation
• DIFFERENT MYOCARDIAL CONTRACTILE PATTERNS BETWEEN THE SUBENDOCARDIUM AND SUBEPICARDIUM INDUCED BY PRESSURE AND VOLUME OVERLOADS AND SOME DRUGS : Ventricular Function : 46th Annual Scientific Meeting, Japanese Circulation Society
• Lisinopril Reduces Left Ventricular Hypertrophy and Cardiac Polyamine Concentrations without a Reduction in Left Ventricular Wall Stress in Transgenic Tsukuba Hypertensive Mice
• CORONARY REPERFUSION 12HOURS AFTER OCCLUSION SIGNIFICANTLY SALVAGED MYOCARDIUM AT THE OUTER LAYER IN DOGS
• RESIDEUAL MYOCARDIAL FLOW AT THE EPICARDIAL RIM AFTER CORONARY OCCLUSION AMOUNTED 75% OF PREOCCLUSION IN DOGS
• THE ROLE OF VASOMOTOR TONE IN SPONTANEOUS RECANALIZATION(SR)OF INFARCT-RELATED ARTERY DURING EVOLVING MYOCARDIAL INFARCTION
• RESIDUAL CRITICAL CORONARY STENOSIS DURING MYOCARDIAL REPERFUSION IS DELETERIOUS TO MYOCARDIAL SALVAGE IN DOGS
• THE IMPORTANCE OF GOOD ENDOCARDIAL REFLOW IMMEDIATELY AFTER REPERFUSION FOR MYOCARDIAL SALVAGE IN DOGS
• EFFECTS OF RESIDUAL CORONARY STENOSIS ON MYOCARDIAL SALVAGE AFTER REPERFUSION IN DOGS
• 0776 COMPARISON OF INTRAVENOUS t-PA AND CONSERVATIVE THERAPY FOR ACUTE MYOCARDIAL INFARCTION IN MULTICENTER TRIAL : RESULTS OF THE SOUTH OSAKA MYOCARDIAL INFARCTION-1(SOMI-1)TRIAL
• -22-THE RELATIONSHIP BETWEEN THE ARACHIDONIC ACID METABOLISM AND THE PLATELET FUCTION IN ISCHEMIC HEART DISEASE
• -0164-RELATIONSHIP BETWEEN ELECTROCARDIOGRAPHIC ST-SEGMENT RE-ELEVATION IN SUBACUTE PHASE AND LEFT VENTRICULAR ASYNERGY IN MYOCARDIAL INFARCTION
• EFFECTS OF MANNITOL IN THE PREVENTION OF EVOLVING MYOCARDIAL INFARCTION
• PARADOXICAL FALL OF TACHYCARDIA- AND HYPOXIA-INDUCED CORONARY FLOW UNDER CONDITIONS OF SEVERE CORONARY STENOSIS IN DOGS
• -P5- BIPHASIC INCREASES OF LEFT VENTRICULAR WALL THICKNESS AFTER CORONARY REPERFUSION IN DOGS : Coronary Thrombosis : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Impairment of regional left ventricular diastolic filling in myocardial infarction
• -0532- COMPARISON OF INTRAVENOUS t-PA AND CONSERVATIVE THERAPY FOR ACUTE MYOCARDIAL INFARCTION IN MULTICENTER TRIAL : RESULTS OF THE SOUTH OSAKA MYOCARDIAL INFARCTION(SOMI)TRIAL(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION
• COMPARISON OF INTRAVENOUS t-PA AND CONSERVATIVE THERAPY FOR ACUTE MYOCARDIAL INFARCTION IN MULTICENTER TRIAL : RESULTS OF THE SOUTH OSAKA MYOCARDIAL INFARCTION (SOMI TRIAL)
• ST-SEGMENT RE-ELEVATION AND LEFT VENTRICULAR EXPANSION SOON AFTER ACUTE ANTERIOR MYOCARDIAL INFARCTION
• -0875-MYOCARDIAL SALVAGE AND REGIONAL MYOCARDIAL FLOW INCREASE AFTER CORONARY REPERFUSION AS MEASURED BY NONRADIOACTIVE COLORED MICROSPHERE : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -0743-CORRELATION BETWEEN MYOCARDIAL CREATINE PHOSPHOKINASE RELEASE AND REGIONAL MYOCARDIAL BLOOD FLOW DURING CORONARY OCCLUSION
• EFFECTS OF RESIDUAL STENOSIS AFTER CORONARY REPERFUSION ON MYOCARDIAL SALVAGE IN DOGS : Coronary Thrombolysis : 53 Annual Scientific Meeting, Japanese Circulation Society
• The Efficacy of Oxygen Inhalation on Acutely-Induced Ischemic Myocardium in Dogs
• Improved prognosis after coronary thrombolysis with urokinase in acute myocardial infarction.

もっと見る 閉じる

スポンサーリンク