THE RELATIONSHIP BETWEEN SERUM LIPOPROTEIN(a) AND RESTENOSIS AFTER INITIAL ELECTIVE PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY
スポンサーリンク
概要
- 論文の詳細を見る
The purpose of this study was to elucidate the possible link between lipoprotein(a) (Lp(a)) and the occurrence of restenosis after initial elective percutaneous transluminal coronary angiopasty (PTCA). Serum lipids, including Lp(a), total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, apolipoprotein A-I (Apo A-I), and apolipoprotein B (Apo B), and the Apo B/Apo A-I ratio were examined in 63 consecutive patients (41 men and 22 women, average age 63±8 years) who underwent initial elective PTCA in our department. Forty two target lesions were in left anterior descending, 10 were in left circumflex and 11 were in right coronary branches. Restenosis was observed in 22 patients (35%) 6.4±2.6 months after PTCA. The serum Lp(a) level was significantly higher in the restenosis group than in the non-restenosis group (38.0 vs 19.9 mg/dl, p<0.05). A significant correlation was observed between serum Lp(a) levels and the degree of % restenosis after PTCA (r=0.557, p<0.001). However, other lipids showed no significant relationship to restenosis. In addition, the % stenosis before PTCA was found to be related to the occurrence of restenosis after successful PTCA. We conclude that the serum Lp(a) level has a close correlation with the degree of % restenosis after PTCA, and may be a useful index for predicting the possibility of restenosis after PTCA, especially in patients with an Lp(a) level above 30 mg/dl.
- 社団法人日本循環器学会の論文
- 1993-07-20
著者
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Hara Masahide
Department of Internal Medicine 1, Faculty of Medicine, Oita University
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Saikawa Tetsunori
Department of Laboratory Examination and Diagnostics, Faculty of Medicine, Oita University
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INOUE Takeshi
Departments of Pathology, Osaka City General Hospital
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Maeda Toshihiro
Department of Cardiology, Komatsushima Red Cross Hospital
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Shimoyama Nobuo
Department of Cardiovascular Medicine, Kumamoto University School of Medicine
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SATO Yasufumi
Department of Vascular Biology, Institute of Development, Aging and Cancer, Tohoku University
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Shimoyama Nobuo
Department Of Internal Medicine Oita Medical University
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Saikawa Tetsunori
Department Of Cardiovascular Science Faculty Of Medicine Oita University
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Sato Yasufumi
Department Of Medicine Oita Medical University
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TENDA KOHJI
Department of Medicine, Oita Medical University
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NIWA HIROKO
Department of Medicine, Oita National Hospital
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YONEMOCHI HIDETOSHI
Department of Medicine, Oita Medical University
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MARUYAMA TOHRU
First Department of Internal Medicine, Kyushu University
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ARAGAKI SATOSHI
Department of Medicine, Oita Medical University
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TAKAKI RYOSABURO
Department of Medicine, Oita Medical University
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Tenda Kohji
Department Of Medicine Oita Medical University
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Maruyama Tohru
First Department Of Internal Medicine Kyushu University
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Niwa Hiroko
Department Of Medicine Oita National Hospital
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Sato Yasufumi
Department Of Internal Medicine 1 Oita Medical University
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Aragaki Satoshi
Department Of Medicine Oita Medical University
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Maeda Toshihiro
Department Of Internal Medicine Oita Medical University
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Maeda Toshihiro
Department Of Anatomy Of Shiga University Of Medical Science
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Takaki Ryosaburo
Department Of Internal Medicine Oita Medical University
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Yonemochi Hidetoshi
Department Of Bioclimatology And Medicine Medical Institute Of Bioregulation Kyushu University
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Hara Masahide
Department Of Internal Medicine 1 Faculty Of Medicine Oita University
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Inoue Toshio
Department Of Internal Medicine Oita Medical University
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Inoue Takeshi
Department Of Biological Sciences Graduate School Of Science The University Of Tokyo
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Inoue Takeshi
Department Of Medicine Oita National Hospital
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Inoue Takeshi
Department Of Animal Husbandry Faculty Of Agriculture Tohoku University
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Niwa Hiroko
Department of Internal Medicine, Sugimura Memorial Hospital
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Saikawa Tetsunori
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University
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