Myocardial Structure in Volume-Overloaded Hearts Before and After Valve Replacement : SYMPOSIUM ON LONG-TERM MYOCARDIAL CHANGES IN HEART DISEASES : 49th Annual Scientific Session of the Japanese Circulation Society
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概要
- 論文の詳細を見る
The purpose of this study was to evaluate the histological characteristics of left ventricular muscle in volume-overloaded hearts. A preoperative biopsy was obtained in 31 patients : 14 with mitral regurgitation, 14 with aortic regurgitation and 3 with mitral regurgitation and aortic regurgitation. Postoperative tissue samples were available in 15 patients. Histological findings were correlated with echocardiographic and angiographic data before (preop) and one year after (postop) operation. Myocardial cell diameter was correlated with both the end-diastolic (r=0.77, p < 0.01) and end-systolic (r=0.78, p < 0.01) dimensions of the left ventricle, but was inversely correlated with the end-diastolic was thickness-to-radius (h/R) ratio (r = -0.71, p < 0.01). Percent fibrosis increased proportionally to the diameter (r = 0.42, p < 0.05). For one year after operation, echocardiographic left ventricular dimensions and angiographic left ventricular volumes were significantly reduced (p < 0.05), but in some patients postoperative values remained greater than normal. With regard to left ventricular morphology, myocardial cell diameter and interstitial fibrosis decreased significantly after valve replacement (p < 0.05). However, the myocardial fiber remained hypertrophied and interstitial fibrosis remained above normal after surgery. Thus, postoperative ventricular dilatation was dependent upon the degree of myocardial fiber hypertrophy and interstitial fibrosis.
- 社団法人日本循環器学会の論文
- 1986-10-20
著者
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Eguchi S
Department Of Thoracic And Cardiovascular Surgery Niigata University School Of Medicine
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Fukuda Junichi
The Second Department Of Surgery Niigata University School Of Medicine
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Fukuda Jun-ichi
The Second Department Of Surgery Niigata University School Of Medicine
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EGUCHI SHOJI
Niigata University School of Medicine
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EGUCHI SHOJI
The 2nd Dep. of Surgery
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Hayashi Jun-ichi
The Second Department of Surgery Niigata University School of Medicine
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Eguchi Shoji
The Second Department of Surgery Niigata University School of Medicine
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YOSHIMURA Takao
The Second Department of Surgery, Niigata University School of Medicine
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OHTANI Shin-ichi
The Second Department of Surgery, Niigata University School of Medicine
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YAMAZAKI Yoshihiko
The Second Department of Surgery, Niigata University School of Medicine
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Eguchi S
Department Of Molecular Design And Engineering Nagoya University
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Hayashi Junichi
The Department Of Thoracic And Cardiovascular Surgery Niigata University School Of Medicine
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Ohtani Shinichi
The Department Of Thoracic And Cardiovascular Surgery Niigata University School Of Medicine
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Yamazaki Yoshihiko
The Second Department Of Surgery Niigata University School Of Medicine
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Eguchi Shoji
The Second Department Of Surgery Of Niigata School Of Medicine
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Eguchi Shoji
Dept Of Thoracic And Cardiovascular Surgery Niigata University Hospital
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Eguchi Shoji
Second Department Of Surgery Niigata University School Of Medicine
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Hayashi Jun-ichi
The Second Department Of Surgery University Of Niigata Faculty Of Medicine
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Eguchi Shoji
The Second Department Of Surgery Niigata University
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Eguchi Shoji
Department Of Molecular Design And Engineering Nagoya University
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Otani Shin-ichi
The 2nd Department Of Surgery University Of Niigata
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Yoshimura Takao
The Second Department Of Surgery Niigata University School Of Medicine
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Eguchi Shoji
The 2nd Department Of Surgery Niigata University School Of Medicine
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Otani Shinichi
Cardiovascular Unit Niigata University
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Otani Shin-ichi
The Second Department Of Surgery University Of Niigata Faculty Of Medicine
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Hayashi Jun-ichi
Division Of Thoracic And Cardiovascular Surgery Niigata University Graduate School Of Medical And De
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Hayashi Jun-ichi
Division Of Cardiovascular And Thoracic Surgery Department Of Cardiovascular And Vital Control Gradu
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Hayashi Junichi
Department Of Thoracic And Cardiovascular Surgery Niigata University Graduate School Of Medical And
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Yamazaki Yoshihiko
Department Of Cardiovascular Surgery Nagaoka Red Cross Hospital
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Yamazaki Yoshihiko
Department Of Thoracic And Cardiovascular Surgery Niigata University School Of Medicine
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EGUCHI Shoji
Department of Molecular Design and Engineering, Nagoya University
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